Table 4.

Characteristics of three lines of mutant Nlrc4 transgenic mice

Mouse lineExpression of Nlrc4 (fold increases compared with wild type)Spleen cells (×107)T cells (×107)CD11b+Gr1+ cells (×107)
Wild type15.2 ± 0.30.8 ± 0.10.05 ± 0.01
Line #13.1 ± 0.221.1 ± 1.43.4 ± 0.40.59 ± 0.2
Line #25.2 ± 0.332.1 ± 3.35.4 ± 2.21.2 ± 0.2
Line #34.2 ± 0.327.8 ± 4.54.5 ± 0.40.89 ± 0.1
  • The data were obtained at the age of 16 wk. The data in line #1 are used in all figures.