Table IV.

Increased IR-induced chromosomal anomalies in hypomorphic Artemis-P70 MEFs

Type of anomalyArt+/+ArtP70/P70Art−/−
Chromosome/chromatid breaks157350
Fusions71611
Radial structure040
Ring structure6613
Unusual structures21318
Total anomalies3010892
Chromosomes scored2,0532,5851,541
Metaphases scored545851
Number of anomalies per chromosome0.0150.0420.060
Number of anomalies per metaphase0.561.861.80