Table I.

Analysis of primed and antigen-challenged wild-type mice and naive mice given recombinant IL-13

ChallengeMiceView fieldsScore of 3
Asp Aga38
 (primed)1,009
 (27 per mouse)459
 (45%)
OVAa22
 (primed)635
 (29 per mouse)198
 (31%)
IL-13b10
 (naive)197
 (20 per mouse)0
  • The number of mice examined, the number of microscopic view fields scored (total number and mean number per mouse), and the number and percentage of view fields given the score of 3 for severe degree of pulmonary arterial muscularization are shown.

  • a Primed wild-type mice were challenged with antigen and given nothing or control antibody.

  • b Naive wild-type mice were challenged with recombinant IL-13.