Table I.

IL-8 and IFN-α levels are highly elevated in sera from eAg-CHB patients with flares

Median of peak cytokine
 concentration (pg/mL)
CHB patientsHealthy controlsp-values
IL-863013<0.0001
IL-1β79blq0.07
IL-611blq0.08
IL-1091.70.04
TNF4blq0.64
IL-12p70172.60.1
IFN-α253200.005
  • The median value is that of the maximum cytokine concentration obtained from 12 CHB patients undergoing flares of liver inflammation and 14 healthy control donors. Significance testing was performed using the Mann-Whitney U test, with those of statistical significance highlighted in bold. blq, below level of quantification.