Table I.

Stroma and timing are critical for complete elimination of established tumors

TreatmentHostTumor
 stromaRejection of
 tumorsap-value
Irradiation + T cells
     2 d later    OT-1H-2b12/12
Irradiation + T cells
     4 d later    OT-1H-2b0/90.001b
Irradiation + T cells
     2 d laterC3H Rag2−/−H-2k0/90.001b
Gemcitabine + T cells
     2 d later    OT-1H-2b7/8
Gemcitabine + T cells
     4 d later    OT-1H-2b0/60.001c
Gemcitabine + T cells
     2 d laterC3H Rag2−/−H-2k0/60.001c
  • a Data are pooled from seven independent experiments. Mice shown in Fig. 3 and Fig. 4 b are included in this pool of data.

  • b Compared, respectively, with the group OT-1 irradiation + T cells 2 d later.

  • c Compared, respectively, with the group OT-1 Gemcitabine + T cells 2 d later.