Table I.

Dimensions of endothelial cells of mouse lymphatics and blood vessels

Initial lymphaticsCollecting
 lymphaticsVenules
Vessel diameter (μm)56 ± 1.5 (baseline) 68 ± 1.3 (LPS)64 ± 722 ± 1**
Cell length (μm)49 ± 166 ± 3*40 ± 3**
Cell width (μm)18 ± 0.814 ± 0.6*11 ± 0.6**
Cell area (μm2)616 ± 40630 ± 40312 ± 19**
  • Measured in mouse tracheal whole mounts stained immunohistochemically for CD31 and LYVE-1 or VE-cadherin. All measurements were made under baseline conditions except for diameter of initial lymphatics, which were prepared under baseline conditions or 24 h after LPS. *, P < 0.05 compared with initial lymphatics; **, P < 0.05 compared with initial lymphatics and collecting lymphatics.