Table I.

Analysis of Y. pseudotuberculosis infection in murine tissues

A. Effect of LTβ−/− mutation on bacterial yields in liver and spleen
SpleenLiver
OrganC57BL/6LTβ−/−C57BL/6LTβ−/−
Range CFU/g tissue102–2 × 05101–3 × 105101–105101–2 × 105
Median CFU/g tissue1.5 × 051.8 × 1024.4 × 1044.2 × 102
p-value0.0020.04
B. Y. pseudotuberculosis clone and CFU distributions in C57BL/6J mice
Hours after inoculation0.55112472180
No. of clones in intestine
    median33.032.032.013.514.08.5
    rangeall at 33all at 32all at 324–297–304–19
No. of clones in liver
    median0.00.00.00.00.51.0
    range0–110–4all at 00–30–160–8
CFU in intestine
    median8 × 107107ND2 × 1046.5 × 1055 × 104
    range7 × 105–9 × 1076 × 106–3 × 107ND2 × 103–105104–1079 × 102–105
CFU in liver
    median0.4 × 1010.00.0ND1.1 × 1025 × 103
    range0–2 × 1010–2 × 1010ND0–1 × 1050–7 × 104