Table I.

Frequency of CD19+ Cells Responsive to S17 + KL + IL-7 or IL-7 Alone

Culture conditions
ExperimentSampleS17 + KL + IL-7IL-7
1E47+/−;GFP1:171:43
E47−/−;EBF1:301:280
2E47+/−;GFP<1:10a1:21
E47−/−;EBF<1:10a1:204
3E47+/−;GFP1:20ND
E47−/−;EBF1:35ND
  • a All wells were positive when plated at 10 cells/well.

  • The frequency was determined as the average number of cells per well, where 37% of wells were nonresponding. For each determination, three cell concentrations were plated with a minimum of 48 wells each.