Table III.

TLR5 SNP Allele and Haplotype Frequencies in Cases and Controls

SNPCases
 n = 108All controls
 n = 508Matched controls
 n = 89
No.BPAllelefreqfreqOR(95% CI)PfreqOR(95% CI)P
1.1174C00.9170.9500.955
1174T10.0830.0501.75(1.00, 3.05)0.050.0451.93(0.74, 5.03)0.18
2.1775A00.8270.8840.899
1775G10.1730.1161.60(1.04, 2.45)0.030.1011.83(1.02, 3.28)0.04
3.1846T00.5200.5200.540
1846C10.4800.4801.00(0.72, 1.38)0.980.4601.09(0.71, 1.68)0.70
Haplotype 1174-1775
CA000.7440.83510.8611
CG010.1730.1151.68(1.10, 2.59)0.020.0942.11(1.16, 3.85)0.02
TA100.0830.0491.90(1.07, 3.35)0.030.0382.53(0.86, 7.49)0.09
TG11000
  • 0 represents the common allele at each locus; 1 is the uncommon allele. Haplotype alleles for SNP1 (1174) and SNP2 (1775) are listed in order. Odds ratio (OR) and 95% confidence intervals represent a comparison of the cases with the two respective control groups with an unadjusted analysis.