Table II.

Passive Protection of Infant Rats Challenged with 5 × 107 CFU of Serogroup C Strain 4243

PretreatmentDose of Ab
 (100 μl per rat)
 or
 serum dilutionNo.
 bacteremia/totalCFU/ml
 (geometric
 mean)
PBS5/5450,000
Neg. control serum1:105/5500,000
Anti-PorA
   (mAb (P1.2)2.0 μg1/53
Anti-GNA18701:10
 1:500/5
 0/4<1
 <1
  • Blood cultures were obtained 18 h after challenge.