Table II.

Hematologic Parameters in wt and ΔdblGATA Mice With or Without an IL-5 Transgene

SexdblGATA GenotypeIL-5 TgWBCManual EO
103/μl%
Fhet5.761
Fhet+43.343
Fhet+24.8310
Mwt+29.410
Mwt+75.699
Mhem8.310
Mhem+50.350
Mhem+46.650
  • Automated measurement of blood from adult wt and ΔdblGATA mutant mouse littermates from a cross between heterozygous ΔdblGATA mutant female and a male heterozygous for an IL-5 transgene (see text for details). For an explanation of abbreviations, see Table I. The IL-5 transgene stimulates eosinophilia in heterozygous females and wt males but not in male mice hemizygous for the ΔdblGATA mutant allele. Manual EO, manual differential count of eosinophils by a blinded observer; WBC, leukocyte count.