Table 1

Comparative Virulence in NMRI Mice of S. aureus Newman Wild Type and mprF Mutant

StrainDays after infectionMortalityArthritisWeight lossBacterial loads in kidneys
no. dead mice/total no.no. positive mice/total no.g×108 CFU
Wild type32/2412/225.1 ± 1.0ND
mprF mutant30/245/241.9 ± 1.8ND
Wild type78/2415/168.4 ± 1.75.9 ± 4.9
mprF mutant70/245/244.1 ± 2.71.1 ± 1.3