Table 2

Preventive Administration of Rosiglitazone or Troglitazone Have Similar Therapeutic Effects on Colitis 2 d after TNBS Administration

Control (n = 16)TNBS (n = 23)Rosiglitazone (n = 14)on TNBS-induced colitisTroglitazone (n = 8)on TNBS-induced colitis
Mortality0%22 ± 6%12.5 ± 12.5%10.2 ± 8%
Wallace score0 ± 07.14 ± 0.863.6 ± 23.8 ± 1.5
Ameho score0 ± 05.5 ± 0.52.3 ± 1.22.5 ± 1
MPO values2.5 ± 3.634 ± 1614 ± 2018 ± 14
TNF-α mRNA0.84 ± 0.813.91 ± 3.940.58 ± 0.690.45 ± 0.74
IL-1β mRNA0.32 ± 0.2628.5 ± 31.14 ± 34 ± 4