Table 3

Influence of HAART on CMV-specific CD8 T Cell Cytokine Expression

Percentage of positive cells
Patient (HLA type)Months of treatmentTetramer positive in CD8+IFN-γ positiveMIP-1β positiveTNF-α positive
897 (A2)01.4666249
62.8706147
102.4746550
132.2847762
912 (A2)01.5747342
61.2817150
913 (A2)03.3555339
164898366
1002 (A2)50.6615837
110.2656450
170.3636450
230.3707040
310.5736545
1003 (B7)122.3767356
313.5756067
1010 (B7)43.3747046
173.4747054
242.9606640
313.5676845
2002 (A2)55.5838360
176.4807858
235798755
29889ND71
2003 (B7)115.6778028
215.8887860
  • Intracellular staining for IFN-γ, MIP-1β, and TNF-α was carried out in combination with tetramer staining using samples from HAART-treated HIV-infected patients. The table shows the cytokine expression and tetramer numbers in CMV-specific CD8+ T cells stimulated with specific peptides.