Table 1

Production of IL-12 p70, IL-4, and IL-10 by FSDCs and Purified DCs upon Phagocytosis of C. albicans Yeasts or Hyphae

IL-12 p70IL-4IL-10
CellsExposure to:6 h48 h6 h48 h6 h48 h
ng/mlng/mlng/ml
FSDCsNone<0.01<0.01<2<2<2<2
FSDCsCandida yeasts2.4 ± 0.73.1 ± 0.7<2<2<2<2
FSDCsCandida yeasts2.0 ± 0.83.5 ± 0.5<2<2<2<2
FSDCsCandida hyphae<0.01<0.0129 ± 625 ± 5<2<2
DCsNone<0.01<0.01<2<2<2<2
DCsCandida yeasts2.1 ± 0.82.7 ± 0.3<2<2<2<2
DCsCandida hyphae<0.01<0.0116 ± 323 ± 4<2<2
  • Values indicated by “<” were below the limit of the assays, as per the manufacturer's indications (see Materials and Methods).