Table 2

Treatment of B16-BL6 Using Anti–CTLA-4 Facilitates Development of Memory to Rechallenge

Primary treatmentTumor incidence at secondary challenge
B16-BL6B16-F0
Experiment 1 (rechallenge on day 128)
BL6/GM plus hamster IgG2/20/2
BL6/GM plus anti–CTLA-42/9*0/9
None5/55/5
Experiment 2 (rechallenge on day 100–130)
BL6/GM plus hamster IgG2/6
BL6/GM plus anti–CTLA-42/15
None5/5