Table 2

Isotype Switching Is Decreased in MMR-deficient IgM+IgD+ Mature B Cells

Percentage of B cellsPercentage of wt switching
IgM+IgD+IgG1 (LPS + IL-4)IgG3 (LPS)IgG2b (LPS + DS)IgG2b (LPS + TGF-β)
Msh2T-depleted624858
IgM+IgD+7988554466
Mlh1T-depleted
IgM+IgD+806188
Pms2T-depleted
IgM+IgD+716955
Mlh1/Pms2T-depleted474828
IgM+IgD+85503144
WtT-depleted100100100100
IgM+IgD+88100100100100