Table II

Trx Does Not Induce Increase of Ca2+ in Single Monocytes and PMNs

Responsive cellsMean Ca2+ increase
Monocytes%
 Trx 0.83–8.3 nM  00
 MCP-1 3 nM 82227 ± 81
 FMLP 100 nM100310 ± 41
PMNs
 Trx 0.83–8.3 nM  00
 IL-8 3 nM 67218 ± 64
 FMLP 100 nM100260 ± 103
  • Data are cumulative of 15–30 cells analyzed. Cells were considered responsive when the stimulus-induced increase of [Ca2+]i was twice the SD over the mean of baseline values. Mean Ca2+ increase is the mean ± SD of values of responsive cells. Data are expressed as percentage above basal [Ca2+]i.