Table 1

Extracellular Production of MCP-1 after HCMV Infection of Fibroblasts

FibroblastsExtracellular production of MCP-1
0–8 h‡8–24 h‡24–48 h‡48–72 h‡
pg/ml
 Uninfected 5,61511,840 9,93810,879
 Virus-free supernatant10,01610,73810,97212,131
Infected with:
 UV-inactivated 9,90610,57210,88910,555
 Heat-inactivated10,94610,55110,13612,021
 Pelleted virus 8,992 9,377 5,329 1,157
 Whole inoculum10,81110,000 4,301          570
  • *  Representative of two experiments.  

  •  Time intervals at which supernatants were collected. At each time interval, cells were washed and re-fed growth medium.