Table 1

Effect of LTA and PepG from S. aureus or B. subtilis on Nitrite Formation in Macrophages

ComponentNitrite formation at concentration (μg/ml)
0.010.111030
μMμMμMμMμM
S. aureus LTA1.8 ± 0.214.0 ± 2.3*39.9 ± 1.2*51.6 ± 1.2*56.8 ± 1.7*
S. aureus PepG1.4 ± 0.22.0 ± 0.1 2.1 ± 0.32.9 ± 0.4 3.3 ± 0.8
B. subtilis LTA 1.9 ± 0.11.7 ± 0.1 2.1 ± 0.22.4 ± 0.2 5.7 ± 1.1
B. subtilis PepG2.0 ± 0.11.5 ± 0.1 2.1 ± 0.26.6 ± 0.217.0 ± 0.9*
  • Data are given as mean ± SE of 12 wells from four independent experiments.  

  • *P <0.05 compared with untreated cells (Dunnett's test).