Table 2

OVA-induced Leukocyte Infiltration in the Lung Interstitium after Chemokine Blockage

Chemokine blockagePercent decrease in area covered by infiltrate
Control0
αEotaxin        90 ± 6
αMCP-5        75 ± 9
Met-RANTES73 ± 13
MIP-1α        21 ± 5
αMCP-197 ± 23
  • Lung sections were obtained 3 h after OVA treatment on day 21 (Control), and the area covered by infiltrate was measured as described in Materials and Methods. Values after each chemokine blockage are given as percent decrease from control mice.