Table 1

IL-6 Serum Levels of TNF-α Transgenic and Wild-type Mice at Different Weeks of Age

MiceIL-6*
7 wk9 wk11 wk
U/ml
TNF-α (n = 8)67.65 ± 11.7456.44 ± 19.1455.25 ± 5.28
Wild type (n = 11)20.93 ± 4.4020.01 ± 1.4424.68 ± 2.20
(P <0.01)(P <0.02)(P <0.001)
  • *  Mean values ± SE. IL-6 activity was measured by hybridoma growth assay and P values were calculated by ANOVA.