Table 1

Magnitude and Protective Capacity of H-2 Db–restricted CTLs Specific for LCMV Peptides NP396-404, GP33-41, and GP276-286

Characteristics of LCMV-specific CTLsHierarchy
Peptide density on infected MC57 cellsGP33-41 > NP396-404 > GP276-286
Magnitude of CTL activity stimulated by LCMV infectionGP33-41 > NP396-404 > GP276-286
Protective capacity of peptide-specific CTLs in C57BL/6 miceNP396-404 > GP276-286 > GP33-41
Protective capacity of peptide-specific CTLs in IFN-γR/ MiceNP396-404 > GP33-41 ≥ GP276-286