Table 2

Edema Accumulation in WT and CD18−/− Mice

WTCD18−/−
Dermatitis  (percent increase in ear width)
 Croton oil, 6 h41.8 ± 3.417.8 ± 8.7*
Pneumonia (μl/lung)
E. coli 6 h78.1 ± 21.5 96.6 ± 15.3
S. pneumoniae 6 h54.9 ± 12.1129.2 ± 24.0*
S. pneumoniae peritonitis  (%125I-albumin recovered)
 4 h 2.7 ± 0.7 1.4 ± 0.3
 24 h 1.2 ± 0.12.6 ± 0.4*
Thioglycollate peritonitis  (%125I-albumin recovered)
 4 h 4.0 ± 1.12.5 ± 0.5
 24 h 1.6 ± 0.25.8 ± 1.2*
  • Edema accumulation was quantified during dermatitis, pneumonia, or peritonitis, as described in the text. Values represent mean ± SEM.  

  • *  Significantly different from WT (P <0.05).