Table 1. Immunological characteristics of patients
P1P2
Age 6 yrAge 26 yrAge 14 yr
Absolute lymphocyte count (×109/liter)2.4 (1.1–4.5)1.74 (1.1–4.5)1.48 (1.1–4.5)
CD3+ T cells
 Absolute (×109/liter)1.7 (0.75–2.51)1.43 (0.75–2.51)1.11 (0.75–2.51)
 %71 (55–84)82.3 (55–84)75 (55–84)
CD4+ T cells
 Absolute (×109/liter)0.94 (0.43–1.69)0.82 (0.43–1.69)0.66 (0.43–1.69)
 %39 (31–60)47.1 (31–60)45 (31–60)
CD8+ T cells
 Absolute (×109/liter)0.67 (0.22–1.21)0.52 (0.22–1.21)0.47 (0.22–1.21)
 %28 (13–41)30.1 (13–41)32 (13–41)
CD16+/CD56+ NK cells
 Absolute (×109/liter)0.12 (0.12–0.60)0.09 (0.12–0.60)0.07 (0.12–0.60)
 %5 (5–27)4.9 (5–27)5 (5–27)
CD19+ B cells
 Absolute (×109/liter)0.48 (0.12–0.64)0.23 (0.12–0.64)0.21 (0.12–0.64)
 %20 (6–25)13.3 (6–25)14 (6–25)
IgE (KU/liter)859 (0–48)7,060 (0–81)795 (0–81)
IgG (g/liter)4.5 (4.9–16.1)7.71 (6–16)5.3 (6–16)
IgG1 (g/liter)4 (2.3–6.4)
IgG2 (g/liter)0.28 (0.4–4.5)
IgG3 (g/liter)0.78 (0.1–1.1)
IgG4 (g/liter)<0.02 (0–0.8)
IgM (g/liter)0.5 (0.5–1.9)0.24 (0.5–1.9)0.3 (0.5–1.9)
IgA (g/liter)0.3 (0.4–2.0)0.91 (0.8–2.8)0.6 (0.8–2.8)
Hib IgG (µg/ml)<0.15 (prevaccine)a3.01a
Pneumococcal titer (IU/ml)38b
Tetanus IgG (IU/ml)>0.1c
NBT (%)0/96100
DHR
 Resting (%)6 (Control, 2)
 Stimulated (%)100 (Control, 100)
IL-6 (pg/ml)830.8 (0–7)
IL-6 (pg/ml)205.6 (0–7)

Abnormal results are shown in bold. Numbers in parentheses indicate reference values of the corresponding measurements. DHR, dihydrorhodamine; Hib, H. influenza bacteria; NBT, nitroblue tetrazolium.

  • a Minimum protective level, 0.15 µg/ml; optimum protective level, 1.0 µg/ml.

  • b A value of 60 represents the 25th centile of the normal population.

  • c Minimum protective level, 0.01 IU/ml; optimum protective level, 0.1 IU/ml; long-term protective level, >1.0 IU/ml.