Table 1. Analgesic ED50 values for oral administration of NIBR14 or FTY720 in bortezomib-induced neuropathic pain (day 25)
TreatmentPain behaviorED5095% CIn
μmol/kg
NIBR14Allodynia21–36
Hyperalgesia21–36
FTY720Allodynia0.090.06–0.23–11
Hyperalgesia0.090.06–0.13–11