RT Journal Article SR Electronic T1 Lymph nodes go with the flow JF The Journal of Experimental Medicine JO J Exp Med FD Rockefeller University Press SP 2699 OP 2701 DO 10.1084/jem.20181898 VO 215 IS 11 A1 Czepielewski, Rafael S. A1 Randolph, Gwendalyn J. YR 2018 UL http://jem.rupress.org/content/215/11/2699.abstract AB In this issue, Bovay et al. (https://doi.org/10.1084/jem.20180217) invoke a compelling model of interplay between the venous and lymphatic vasculature in regulating the developmental genesis and early expansion of LNs. This work supports an emerging model that lymph–venous crosstalk supports LN functionality at all stages.