JEM -- Table of Contents (206 [6])

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Jun 8 2009; 206 (6)

       IN THIS ISSUE

       PEOPLE & IDEAS

       COMMENTARIES

       BRIEF DEFINITIVE REPORTS

       ARTICLES

       FROM THE JCB

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To see an article, click its [Full Text] or [PDF] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.
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PODCAST:

June 1, 2009 Heart muscle actin replaces skeletal muscle actin; How parasites have shaped our interleukin genes; Decorin's anti-tumor effect

IN THIS ISSUE:

IN THIS ISSUE [PDF]

TLR choreography [Full Text]

Galvanizing allergies [Full Text]

IL-17 propels infection [Full Text]

Interleukins adapt to parasites [Full Text]

Modeling MS [Full Text]

PEOPLE & IDEAS:

Matthew Krummel: Visions enumerated

Amy Maxmen
J. Exp. Med. 2009 206: 1212-1213. Published online Jun 8 2009, 10.1084/jem.2066pi. [Full Text] [PDF (686K)]

COMMENTARIES:

Tracking the culprit: HIV-1 evolution and immune selection revealed by single-genome amplification

Zabrina L. Brumme and Bruce D. Walker
J. Exp. Med. 2009 206: 1215-1218. Published online Jun 1 2009, 10.1084/jem.20091094. [Abstract] [Full Text] [PDF (918K)]

BRIEF DEFINITIVE REPORTS:

Inhibition of NK cell activity by IL-17 allows vaccinia virus to induce severe skin lesions in a mouse model of eczema vaccinatum

Yuko Kawakami, Yoshiaki Tomimori, Kenji Yumoto, Shunji Hasegawa, Tomoaki Ando, Yutaka Tagaya, Shane Crotty, and Toshiaki Kawakami
J. Exp. Med. 2009 206: 1219-1225. Published online May 25 2009, 10.1084/jem.20082835. [Abstract] [Full Text] [PDF (2349K)] [PDF+supp data (3796K)] [Supplemental Material Index]

Cholera toxin inhibits IL-12 production and CD8 ${alpha}$ ⁺ dendritic cell differentiation by cAMP-mediated inhibition of IRF8 function

Andrea la Sala, Jianping He, Leopoldo Laricchia-Robbio, Stefania Gorini, Akiko Iwasaki, Michael Braun, George S. Yap, Alan Sher, Keiko Ozato, and Brian Kelsall
J. Exp. Med. 2009 206: 1227-1235. Published online Jun 1 2009, 10.1084/jem.20080912. [Abstract] [Full Text] [PDF (4573K)] [PDF+supp data (6015K)] [Supplemental Material Index]

Immunoglobulin switch µ sequence causes RNA polymerase II accumulation and reduces dA hypermutation

Deepa Rajagopal, Robert W. Maul, Amalendu Ghosh, Tirtha Chakraborty, Ahmed Amine Khamlichi, Ranjan Sen, and Patricia J. Gearhart
J. Exp. Med. 2009 206: 1237-1244. Published online May 11 2009, 10.1084/jem.20082514. [Abstract] [Full Text] [PDF (2770K)] [PDF+supp data (5537K)] [Supplemental Material Index]

Neonatal tolerance revisited: a perinatal window for Aire control of autoimmunity

Mireia Guerau-de-Arellano, Marianne Martinic, Christophe Benoist, and Diane Mathis
J. Exp. Med. 2009 206: 1245-1252. Published online Jun 1 2009, 10.1084/jem.20090300. [Abstract] [Full Text] [PDF (4518K)] [PDF+supp data (5678K)] [Supplemental Material Index]

ARTICLES:

The first T cell response to transmitted/founder virus contributes to the control of acute viremia in HIV-1 infection

Nilu Goonetilleke, Michael K.P. Liu, Jesus F. Salazar-Gonzalez, Guido Ferrari, Elena Giorgi, Vitaly V. Ganusov, Brandon F. Keele, Gerald H. Learn, Emma L. Turnbull, Maria G. Salazar, Kent J. Weinhold, Stephen Moore, CHAVI Clinical Core B, Norman Letvin, Barton F. Haynes, Myron S. Cohen, Peter Hraber, Tanmoy Bhattacharya, Persephone Borrow, Alan S. Perelson, Beatrice H. Hahn, George M. Shaw, Bette T. Korber, and Andrew J. McMichael
J. Exp. Med. 2009 206: 1253-1272. Published online Jun 1 2009, 10.1084/jem.20090365. [Abstract] [Full Text] [PDF (9574K)] [PDF+supp data (11985K)] [Supplemental Material Index]

Genetic identity, biological phenotype, and evolutionary pathways of transmitted/founder viruses in acute and early HIV-1 infection

Jesus F. Salazar-Gonzalez, Maria G. Salazar, Brandon F. Keele, Gerald H. Learn, Elena E. Giorgi, Hui Li, Julie M. Decker, Shuyi Wang, Joshua Baalwa, Matthias H. Kraus, Nicholas F. Parrish, Katharina S. Shaw, M. Brad Guffey, Katharine J. Bar, Katie L. Davis, Christina Ochsenbauer-Jambor, John C. Kappes, Michael S. Saag, Myron S. Cohen, Joseph Mulenga, Cynthia A. Derdeyn, Susan Allen, Eric Hunter, Martin Markowitz, Peter Hraber, Alan S. Perelson, Tanmoy Bhattacharya, Barton F. Haynes, Bette T. Korber, Beatrice H. Hahn, and George M. Shaw
J. Exp. Med. 2009 206: 1273-1289. Published online Jun 1 2009, 10.1084/jem.20090378. [Abstract] [Full Text] [PDF (5588K)] [PDF+supp data (7262K)] [Supplemental Material Index]

Molecular explanation for the contradiction between systemic Th17 defect and localized bacterial infection in hyper-IgE syndrome

Yoshiyuki Minegishi, Masako Saito, Masayuki Nagasawa, Hidetoshi Takada, Toshiro Hara, Shigeru Tsuchiya, Kazunaga Agematsu, Masafumi Yamada, Nobuaki Kawamura, Tadashi Ariga, Ikuya Tsuge, and Hajime Karasuyama
J. Exp. Med. 2009 206: 1291-1301. Published online Jun 1 2009, 10.1084/jem.20082767. [Abstract] [Full Text] [PDF (3335K)] [PDF+supp data (7285K)] [Supplemental Material Index]

Spontaneous relapsing-remitting EAE in the SJL/J mouse: MOG-reactive transgenic T cells recruit endogenous MOG-specific B cells

Bernadette Pöllinger, Gurumoorthy Krishnamoorthy, Kerstin Berer, Hans Lassmann, Michael R. Bösl, Robert Dunn, Helena S. Domingues, Andreas Holz, Florian C. Kurschus, and Hartmut Wekerle
J. Exp. Med. 2009 206: 1303-1316. Published online Jun 1 2009, 10.1084/jem.20090299. [Abstract] [Full Text] [PDF (3844K)] [PDF+supp data (5958K)] [Supplemental Material Index]

Milk fat globule epidermal growth factor–8 blockade triggers tumor destruction through coordinated cell-autonomous and immune-mediated mechanisms

Masahisa Jinushi, Marimo Sato, Akira Kanamoto, Akihiko Itoh, Shigenori Nagai, Shigeo Koyasu, Glenn Dranoff, and Hideaki Tahara
J. Exp. Med. 2009 206: 1317-1326. Published online May 11 2009, 10.1084/jem.20082614. [Abstract] [Full Text] [PDF (2628K)] [PDF+supp data (3912K)] [Supplemental Material Index]

Activated monocytes in peritumoral stroma of hepatocellular carcinoma foster immune privilege and disease progression through PD-L1

Dong-Ming Kuang, Qiyi Zhao, Chen Peng, Jing Xu, Jing-Ping Zhang, Changyou Wu, and Limin Zheng
J. Exp. Med. 2009 206: 1327-1337. Published online May 18 2009, 10.1084/jem.20082173. [Abstract] [Full Text] [PDF (4873K)] [PDF+supp data (5948K)] [Supplemental Material Index]

Unc93B1 biases Toll-like receptor responses to nucleic acid in dendritic cells toward DNA- but against RNA-sensing

Ryutaro Fukui, Shin-ichiroh Saitoh, Fumi Matsumoto, Hiroko Kozuka-Hata, Masaaki Oyama, Koichi Tabeta, Bruce Beutler, and Kensuke Miyake
J. Exp. Med. 2009 206: 1339-1350. Published online May 18 2009, 10.1084/jem.20082316. [Abstract] [Full Text] [PDF (4552K)] [PDF+supp data (7853K)] [Supplemental Material Index]

Zinc transporter Znt5/Slc30a5 is required for the mast cell–mediated delayed-type allergic reaction but not the immediate-type reaction

Keigo Nishida, Aiko Hasegawa, Susumu Nakae, Keisuke Oboki, Hirohisa Saito, Satoru Yamasaki, and Toshio Hirano
J. Exp. Med. 2009 206: 1351-1364. Published online May 18 2009, 10.1084/jem.20082533. [Abstract] [Full Text] [PDF (3692K)] [PDF+supp data (5647K)] [Supplemental Material Index]

iNKT cell development is orchestrated by different branches of TGF-β signaling

Jean-Marc Doisne, Laurent Bartholin, Kai-Ping Yan, Céline N. Garcia, Nadia Duarte, Jean-Benoît Le Luduec, David Vincent, Farhan Cyprian, Branka Horvat, Sylvie Martel, Ruth Rimokh, Régine Losson, Kamel Benlagha, and Julien C. Marie
J. Exp. Med. 2009 206: 1365-1378. Published online May 18 2009, 10.1084/jem.20090127. [Abstract] [Full Text] [PDF (6524K)] [PDF+supp data (8259K)] [Supplemental Material Index]

CD95 co-stimulation blocks activation of naive T cells by inhibiting T cell receptor signaling

Gudrun Strauss, Jonathan A. Lindquist, Nathalie Arhel, Edward Felder, Sabine Karl, Tobias L. Haas, Simone Fulda, Henning Walczak, Frank Kirchhoff, and Klaus-Michael Debatin
J. Exp. Med. 2009 206: 1379-1393. Published online Jun 1 2009, 10.1084/jem.20082363. [Abstract] [Full Text] [PDF (7233K)] [PDF+supp data (9479K)] [Supplemental Material Index]

Parasites represent a major selective force for interleukin genes and shape the genetic predisposition to autoimmune conditions

Matteo Fumagalli, Uberto Pozzoli, Rachele Cagliani, Giacomo P. Comi, Stefania Riva, Mario Clerici, Nereo Bresolin, and Manuela Sironi
J. Exp. Med. 2009 206: 1395-1408. Published online May 25 2009, 10.1084/jem.20082779. [Abstract] [Full Text] [PDF (1333K)] [PDF+supp data (10097K)] [Supplemental Material Index][Related biobytes podcast]

CD1c bypasses lysosomes to present a lipopeptide antigen with 12 amino acids

Ildiko Van Rhijn, David C. Young, Annemieke De Jong, Jenny Vazquez, Tan-Yun Cheng, Rahul Talekar, Duarte C. Barral, Luis León, Michael B. Brenner, Joel T. Katz, Richard Riese, Ruth M. Ruprecht, Peter B. O'Connor, Catherine E. Costello, Steven A. Porcelli, Volker Briken, and D. Branch Moody
J. Exp. Med. 2009 206: 1409-1422. Published online May 25 2009, 10.1084/jem.20082480. [Abstract] [Full Text] [PDF (1936K)] [PDF+supp data (2560K)] [Supplemental Material Index]

Priming of protective T cell responses against virus-induced tumors in mice with human immune system components

Till Strowig, Cagan Gurer, Alexander Ploss, Yi-Fang Liu, Frida Arrey, Junji Sashihara, Gloria Koo, Charles M. Rice, James W. Young, Amy Chadburn, Jeffrey I. Cohen, and Christian Münz
J. Exp. Med. 2009 206: 1423-1434. Published online Jun 1 2009, 10.1084/jem.20081720. [Abstract] [Full Text] [PDF (4438K)] [PDF+supp data (10362K)] [Supplemental Material Index]

Deficiency of the DNA repair enzyme ATM in rheumatoid arthritis

Lan Shao, Hiroshi Fujii, Inés Colmegna, Hisashi Oishi, Jörg J. Goronzy, and Cornelia M. Weyand
J. Exp. Med. 2009 206: 1435-1449. Published online May 18 2009, 10.1084/jem.20082251. [Abstract] [Full Text] [PDF (5627K)] [PDF+supp data (7819K)] [Supplemental Material Index]

FROM THE JCB:

VE-PTP controls blood vessel development by balancing Tie-2 activity

Mark Winderlich, Linda Keller, Giuseppe Cagna, Andre Broermann, Olena Kamenyeva, Friedemann Kiefer, Urban Deutsch, Astrid F. Nottebaum, and Dietmar Vestweber [Full Text]

To see an article, click its [Full Text] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.