JEM -- Table of Contents (206 [4])

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Apr 13 2009; 206 (4)

       IN THIS ISSUE

       PEOPLE & IDEAS

       COMMENTARIES

       BRIEF DEFINITIVE REPORTS

       ARTICLES

       FROM THE JCB

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To see an article, click its [Full Text] or [PDF] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.
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PODCAST:

April 6, 2009 Brain development and asymmetric cell division; cell stress; an alternative to immunosuppressive drugs?

IN THIS ISSUE:

IN THIS ISSUE [PDF]

Immune understudies combat lupus [Full Text]

Flipping the cancer switch [Full Text]

Save yourself, cancer cell [Full Text]

Lasting T reg cell–mediated protection [Full Text]

HIV's cost/benefit analysis [Full Text]

PEOPLE & IDEAS:

Dana Philpott: Exploring the land of NOD

Kira Heller
J. Exp. Med. 2009 206: 728-729. Published online Apr 13 2009, 10.1084/jem.2064pi. [Full Text] [PDF (589K)]

COMMENTARIES:

Settling the thymus: immigration requirements

Jason G. Cyster
J. Exp. Med. 2009 206: 731-734. Published online Apr 6 2009, 10.1084/jem.20090458. [Abstract] [Full Text] [PDF (1399K)]

BRIEF DEFINITIVE REPORTS:

The Wiskott-Aldrich syndrome protein is required for iNKT cell maturation and function

Michela Locci, Elena Draghici, Francesco Marangoni, Marita Bosticardo, Marco Catucci, Alessandro Aiuti, Caterina Cancrini, Laszlo Marodi, Teresa Espanol, Robbert G.M. Bredius, Adrian J. Thrasher, Ansgar Schulz, Jiri Litzman, Maria Grazia Roncarolo, Giulia Casorati, Paolo Dellabona, and Anna Villa
J. Exp. Med. 2009 206: 735-742. Published online Mar 23 2009, 10.1084/jem.20081773. [Abstract] [Full Text] [PDF (3574K)] [PDF+supp data (4480K)] [Supplemental Material Index]

A role for human skin–resident T cells in wound healing

Antoine Toulon, Lionel Breton, Kristen R. Taylor, Mayer Tenenhaus, Dhaval Bhavsar, Caroline Lanigan, Ross Rudolph, Julie Jameson, and Wendy L. Havran
J. Exp. Med. 2009 206: 743-750. Published online Mar 23 2009, 10.1084/jem.20081787. [Abstract] [Full Text] [PDF (3153K)] [PDF+supp data (3576K)] [Supplemental Material Index]

In vivo expansion of T reg cells with IL-2–mAb complexes: induction of resistance to EAE and long-term acceptance of islet allografts without immunosuppression

Kylie E. Webster, Stacey Walters, Rachel E. Kohler, Tomas Mrkvan, Onur Boyman, Charles D. Surh, Shane T. Grey, and Jonathan Sprent
J. Exp. Med. 2009 206: 751-760. Published online Mar 30 2009, 10.1084/jem.20082824. [Abstract] [Full Text] [PDF (4474K)] [PDF+supp data (5883K)] [Supplemental Material Index][Related biobytes podcast]

ARTICLES:

Thymic progenitor homing and lymphocyte homeostasis are linked via S1P-controlled expression of thymic P-selectin/CCL25

Klaus Gossens, Silvia Naus, Stephane Y. Corbel, Shujun Lin, Fabio M.V. Rossi, Jürgen Kast, and Hermann J. Ziltener
J. Exp. Med. 2009 206: 761-778. Published online Mar 16 2009, 10.1084/jem.20082502. [Abstract] [Full Text] [PDF (5203K)] [PDF+supp data (6779K)] [Supplemental Material Index]

CSL–MAML-dependent Notch1 signaling controls T lineage–specific IL-7R ${alpha}$ gene expression in early human thymopoiesis and leukemia

Sara González-García, Marina García-Peydró, Enrique Martín-Gayo, Esteban Ballestar, Manel Esteller, Rafael Bornstein, José Luis de la Pompa, Adolfo A. Ferrando, and María L. Toribio
J. Exp. Med. 2009 206: 779-791. Published online Apr 6 2009, 10.1084/jem.20081922. [Abstract] [Full Text] [PDF (4813K)] [PDF+supp data (7713K)] [Supplemental Material Index]

Normally occurring NKG2D⁺CD4⁺ T cells are immunosuppressive and inversely correlated with disease activity in juvenile-onset lupus

Zhenpeng Dai, Cameron J. Turtle, Garrett C. Booth, Stanley R. Riddell, Theodore A. Gooley, Anne M. Stevens, Thomas Spies, and Veronika Groh
J. Exp. Med. 2009 206: 793-805. Published online Mar 16 2009, 10.1084/jem.20081648. [Abstract] [Full Text] [PDF (4623K)]

Ly49H signaling through DAP10 is essential for optimal natural killer cell responses to mouse cytomegalovirus infection

Mark T. Orr, Joseph C. Sun, David G.T. Hesslein, Hisashi Arase, Joseph H. Phillips, Toshiyuki Takai, and Lewis L. Lanier
J. Exp. Med. 2009 206: 807-817. Published online Mar 30 2009, 10.1084/jem.20090168. [Abstract] [Full Text] [PDF (2905K)] [PDF+supp data (5517K)] [Supplemental Material Index]

Loss of STAT5 causes liver fibrosis and cancer development through increased TGF-β and STAT3 activation

Atsushi Hosui, Akiko Kimura, Daisuke Yamaji, Bing-mei Zhu, Risu Na, and Lothar Hennighausen
J. Exp. Med. 2009 206: 819-831. Published online Mar 30 2009, 10.1084/jem.20080003. [Abstract] [Full Text] [PDF (8217K)] [PDF+supp data (13117K)] [Supplemental Material Index]

Netrin-1 acts as a survival factor for aggressive neuroblastoma

Céline Delloye-Bourgeois, Julien Fitamant, Andrea Paradisi, David Cappellen, Setha Douc-Rasy, Marie-Anne Raquin, Dwayne Stupack, Akira Nakagawara, Raphaël Rousseau, Valérie Combaret, Alain Puisieux, Dominique Valteau-Couanet, Jean Bénard, Agnès Bernet, and Patrick Mehlen
J. Exp. Med. 2009 206: 833-847. Published online Apr 6 2009, 10.1084/jem.20082299. [Abstract] [Full Text] [PDF (7311K)] [PDF+supp data (10960K)] [Supplemental Material Index]

Self-antigen–specific CD8⁺ T cell precursor frequency determines the quality of the antitumor immune response

Gabrielle A. Rizzuto, Taha Merghoub, Daniel Hirschhorn-Cymerman, Cailian Liu, Alexander M. Lesokhin, Diana Sahawneh, Hong Zhong, Katherine S. Panageas, Miguel-Angel Perales, Grégoire Altan-Bonnet, Jedd D. Wolchok, and Alan N. Houghton
J. Exp. Med. 2009 206: 849-866. Published online Mar 30 2009, 10.1084/jem.20081382. [Abstract] [Full Text] [PDF (7669K)] [PDF+supp data (12160K)] [Supplemental Material Index]

Transcriptional complexes formed by NFAT dimers regulate the induction of T cell tolerance

Noemi Soto-Nieves, Irene Puga, Brian T. Abe, Sanmay Bandyopadhyay, Ian Baine, Anjana Rao, and Fernando Macian
J. Exp. Med. 2009 206: 867-876. Published online Mar 23 2009, 10.1084/jem.20082731. [Abstract] [Full Text] [PDF (2987K)] [PDF+supp data (4680K)] [Supplemental Material Index]

Control of T helper cell differentiation through cytokine receptor inclusion in the immunological synapse

Roberto A. Maldonado, Michelle A. Soriano, L. Carolina Perdomo, Kirsten Sigrist, Darrell J. Irvine, Thomas Decker, and Laurie H. Glimcher
J. Exp. Med. 2009 206: 877-892. Published online Apr 6 2009, 10.1084/jem.20082900. [Abstract] [Full Text] [PDF (3105K)] [PDF+supp data (4366K)] [Supplemental Material Index]

Impact of a hypomorphic Artemis disease allele on lymphocyte development, DNA end processing, and genome stability

Ying Huang, William Giblin, Martina Kubec, Gerwin Westfield, Jordan St. Charles, Laurel Chadde, Stephanie Kraftson, and JoAnn Sekiguchi
J. Exp. Med. 2009 206: 893-908. Published online Apr 6 2009, 10.1084/jem.20082396. [Abstract] [Full Text] [PDF (5578K)] [PDF+supp data (7537K)] [Supplemental Material Index]

Evolution of HLA-B*5703 HIV-1 escape mutations in HLA-B*5703–positive individuals and their transmission recipients

Hayley Crawford, Wendy Lumm, Alasdair Leslie, Malinda Schaefer, Debrah Boeras, Julia G. Prado, Jianming Tang, Paul Farmer, Thumbi Ndung'u, Shabir Lakhi, Jill Gilmour, Paul Goepfert, Bruce D. Walker, Richard Kaslow, Joseph Mulenga, Susan Allen, Philip J.R. Goulder, and Eric Hunter
J. Exp. Med. 2009 206: 909-921. Published online Mar 23 2009, 10.1084/jem.20081984. [Abstract] [Full Text] [PDF (5252K)]

Public clonotype usage identifies protective Gag-specific CD8⁺ T cell responses in SIV infection

David A. Price, Tedi E. Asher, Nancy A. Wilson, Martha C. Nason, Jason M. Brenchley, Ian S. Metzler, Vanessa Venturi, Emma Gostick, Pratip K. Chattopadhyay, Mario Roederer, Miles P. Davenport, David I. Watkins, and Daniel C. Douek
J. Exp. Med. 2009 206: 923-936. Published online Apr 6 2009, 10.1084/jem.20081127. [Abstract] [Full Text] [PDF (6171K)] [PDF+supp data (11041K)] [Supplemental Material Index]

Alternatively activated macrophage-derived RELM- ${alpha}$ is a negative regulator of type 2 inflammation in the lung

Meera G. Nair, Yurong Du, Jacqueline G. Perrigoue, Colby Zaph, Justin J. Taylor, Michael Goldschmidt, Gary P. Swain, George D. Yancopoulos, David M. Valenzuela, Andrew Murphy, Margaret Karow, Sean Stevens, Edward J. Pearce, and David Artis
J. Exp. Med. 2009 206: 937-952. Published online Apr 6 2009, 10.1084/jem.20082048. [Abstract] [Full Text] [PDF (9162K)] [PDF+supp data (10398K)] [Supplemental Material Index]

Drug inhibition of HDAC3 and epigenetic control of differentiation in Apicomplexa parasites

Alexandre Bougdour, Danièle Maubon, Patricia Baldacci, Philippe Ortet, Olivier Bastien, Anthony Bouillon, Jean-Christophe Barale, Hervé Pelloux, Robert Ménard, and Mohamed-Ali Hakimi
J. Exp. Med. 2009 206: 953-966. Published online Apr 6 2009, 10.1084/jem.20082826. [Abstract] [Full Text] [PDF (4644K)] [PDF+supp data (9400K)] [Supplemental Material Index]

FROM THE JCB:

Regulation of epithelial–mesenchymal IL-1 signaling by PPARβ/ ${delta}$ is essential for skin homeostasis and wound healing

Han Chung Chong, Ming Jie Tan, Virginie Philippe, Siew Hwey Tan, Chek Kun Tan, Chee Wai Ku, Yan Yih Goh, Walter Wahli, Liliane Michalik, and Nguan Soon Tan [Full Text]

Canonical Wnts function as potent regulators of osteogenesis by human mesenchymal stem cells

Guizhong Liu, Sapna Vijayakumar, Luca Grumolato, Randy Arroyave, HuiFang Qiao, Gal Akiri, and Stuart A. Aaronson [Full Text]

To see an article, click its [Full Text] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.