JEM -- Table of Contents (206 [3])

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Mar 16 2009; 206 (3)

       IN THIS ISSUE

       PEOPLE & IDEAS

       BRIEF DEFINITIVE REPORTS

       ARTICLES

       CORRECTIONS

       FROM THE JCB

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To see an article, click its [Full Text] or [PDF] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.
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PODCAST:

March 9, 2009 Neuroprotection by the Wld^s protein; Cancer-blocking systatin.

IN THIS ISSUE:

IN THIS ISSUE [PDF]

New parts in beating hearts [Full Text]

Dendritic cells teach tolerance [Full Text]

Flagging Th17 in Crohn's [Full Text]

TSLP calms inflammation [Full Text]

A syndecan-based tumor stopper [Full Text]

PEOPLE & IDEAS:

Clifton E. Barry, III: TB's strategic opponent

Amy Maxmen
J. Exp. Med. 2009 206: 494-495. Published online Mar 16 2009, 10.1084/jem.2063pi. [Full Text] [PDF (660K)]

BRIEF DEFINITIVE REPORTS:

Identification of antigen-presenting dendritic cells in mouse aorta and cardiac valves

Jae-Hoon Choi, Yoonkyung Do, Cheolho Cheong, Hyein Koh, Silvia B. Boscardin, Yong-Seok Oh, Leonia Bozzacco, Christine Trumpfheller, Chae Gyu Park, and Ralph M. Steinman
J. Exp. Med. 2009 206: 497-505. Published online Feb 16 2009, 10.1084/jem.20082129. [Abstract] [Full Text] [PDF (6434K)] [PDF+supp data (7611K)] [Supplemental Material Index]

A novel myelin P0–specific T cell receptor transgenic mouse develops a fulminant autoimmune peripheral neuropathy

Cédric Louvet, Beniwende G. Kabre, Dan W. Davini, Nicolas Martinier, Maureen A. Su, Jason J. DeVoss, Wendy L. Rosenthal, Mark S. Anderson, Hélène Bour-Jordan, and Jeffrey A. Bluestone
J. Exp. Med. 2009 206: 507-514. Published online Feb 16 2009, 10.1084/jem.20082113. [Abstract] [Full Text] [PDF (1707K)] [PDF+supp data (3725K)] [Supplemental Material Index]

Ly49P recognition of cytomegalovirus-infected cells expressing H2-D^k and CMV-encoded m04 correlates with the NK cell antiviral response

Agnieszka Kielczewska, Michal Pyzik, Tianhe Sun, Astrid Krmpotic, Melissa B. Lodoen, Michael W. Munks, Marina Babic, Ann B. Hill, Ulrich H. Koszinowski, Stipan Jonjic, Lewis L. Lanier, and Silvia M. Vidal
J. Exp. Med. 2009 206: 515-523. Published online Mar 2 2009, 10.1084/jem.20080954. [Abstract] [Full Text] [PDF (3894K)]

Circulating and gut-resident human Th17 cells express CD161 and promote intestinal inflammation

Melanie A. Kleinschek, Katia Boniface, Svetlana Sadekova, Jeff Grein, Erin E. Murphy, Scott P. Turner, Lisa Raskin, Bela Desai, William A. Faubion, Rene de Waal Malefyt, Robert H. Pierce, Terrill McClanahan, and Robert A. Kastelein
J. Exp. Med. 2009 206: 525-534. Published online Mar 9 2009, 10.1084/jem.20081712. [Abstract] [Full Text] [PDF (3750K)] [PDF+supp data (6389K)] [Supplemental Material Index]

ARTICLES:

Prostaglandin E2 regulates Th17 cell differentiation and function through cyclic AMP and EP2/EP4 receptor signaling

Katia Boniface, Kristian S. Bak-Jensen, Ying Li, Wendy M. Blumenschein, Mandy J. McGeachy, Terrill K. McClanahan, Brent S. McKenzie, Robert A. Kastelein, Daniel J. Cua, and René de Waal Malefyt
J. Exp. Med. 2009 206: 535-548. Published online Mar 9 2009, 10.1084/jem.20082293. [Abstract] [Full Text] [PDF (5505K)] [PDF+supp data (6984K)] [Supplemental Material Index]

Constitutive ablation of dendritic cells breaks self-tolerance of CD4 T cells and results in spontaneous fatal autoimmunity

Caspar Ohnmacht, Andrea Pullner, Susan B.S. King, Ingo Drexler, Stefanie Meier, Thomas Brocker, and David Voehringer
J. Exp. Med. 2009 206: 549-559. Published online Feb 23 2009, 10.1084/jem.20082394. [Abstract] [Full Text] [PDF (6272K)] [PDF+supp data (11422K)] [Supplemental Material Index]

Follicular helper T cells are required for systemic autoimmunity

Michelle A. Linterman, Robert J. Rigby, Raphael. K. Wong, Di Yu, Robert Brink, Jennifer L. Cannons, Pamela L. Schwartzberg, Matthew C. Cook, Giles D. Walters, and Carola G. Vinuesa
J. Exp. Med. 2009 206: 561-576. Published online Feb 16 2009, 10.1084/jem.20081886. [Abstract] [Full Text] [PDF (9386K)] [PDF+supp data (11592K)] [Supplemental Material Index]

Critical role of phospholipase C ${gamma}$ 2 in integrin and Fc receptor-mediated neutrophil functions and the effector phase of autoimmune arthritis

Zoltán Jakus, Edina Simon, David Frommhold, Markus Sperandio, and Attila Mócsai
J. Exp. Med. 2009 206: 577-593. Published online Mar 9 2009, 10.1084/jem.20081859. [Abstract] [Full Text] [PDF (7055K)] [PDF+supp data (8075K)] [Supplemental Material Index]

CX₃CR1⁺ CD115⁺ CD135⁺ common macrophage/DC precursors and the role of CX₃CR1 in their response to inflammation

Cedric Auffray, Darin K. Fogg, Emilie Narni-Mancinelli, Brigitte Senechal, Celine Trouillet, Noah Saederup, Julia Leemput, Karine Bigot, Laura Campisi, Marc Abitbol, Thierry Molina, Israel Charo, David A. Hume, Ana Cumano, Gregoire Lauvau, and Frederic Geissmann
J. Exp. Med. 2009 206: 595-606. Published online Mar 9 2009, 10.1084/jem.20081385. [Abstract] [Full Text] [PDF (4672K)] [PDF+supp data (9028K)] [Supplemental Material Index]

Thymus-homing peripheral dendritic cells constitute two of the three major subsets of dendritic cells in the steady-state thymus

JiChu Li, JooHung Park, Deborah Foss, and Irving Goldschneider
J. Exp. Med. 2009 206: 607-622. Published online Mar 9 2009, 10.1084/jem.20082232. [Abstract] [Full Text] [PDF (6615K)]

The adhesion molecule L1 regulates transendothelial migration and trafficking of dendritic cells

Luigi Maddaluno, Sue Ellen Verbrugge, Chiara Martinoli, Gianluca Matteoli, Andrea Chiavelli, Yiping Zeng, Elizabeth D. Williams, Maria Rescigno, and Ugo Cavallaro
J. Exp. Med. 2009 206: 623-635. Published online Mar 9 2009, 10.1084/jem.20081211. [Abstract] [Full Text] [PDF (4843K)] [PDF+supp data (14398K)] [ Supplemental Material Index]

Evolutionarily conserved recognition and innate immunity to fungal pathogens by the scavenger receptors SCARF1 and CD36

Terry K. Means, Eleftherios Mylonakis, Emmanouil Tampakakis, Richard A. Colvin, Edward Seung, Lindsay Puckett, Melissa F. Tai, Cameron R. Stewart, Read Pukkila-Worley, Suzanne E. Hickman, Kathryn J. Moore, Stephen B. Calderwood, Nir Hacohen, Andrew D. Luster, and Joseph El Khoury
J. Exp. Med. 2009 206: 637-653. Published online Feb 23 2009, 10.1084/jem.20082109. [Abstract] [Full Text] [PDF (5835K)] [PDF+supp data (10427K)] [Supplemental Material Index]

TSLP regulates intestinal immunity and inflammation in mouse models of helminth infection and colitis

Betsy C. Taylor, Colby Zaph, Amy E. Troy, Yurong Du, Katherine J. Guild, Michael R. Comeau, and David Artis
J. Exp. Med. 2009 206: 655-667. Published online Mar 9 2009, 10.1084/jem.20081499. [Abstract] [Full Text] [PDF (4705K)] [PDF+supp data (5729K)] [Supplemental Material Index]

MRN complex function in the repair of chromosomal Rag-mediated DNA double-strand breaks

Beth A. Helmink, Andrea L. Bredemeyer, Baeck-Seung Lee, Ching-Yu Huang, Girdhar G. Sharma, Laura M. Walker, Jeffrey J. Bednarski, Wan-Ling Lee, Tej K. Pandita, Craig H. Bassing, and Barry P. Sleckman
J. Exp. Med. 2009 206: 669-679. Published online Feb 16 2009, 10.1084/jem.20081326. [Abstract] [Full Text] [PDF (3223K)] [PDF+supp data (8792K)] [Supplemental Material Index]

PLC- ${gamma}$ 2 is essential for formation and maintenance of memory B cells

Masaki Hikida, Stefano Casola, Noriko Takahashi, Tomohiro Kaji, Toshitada Takemori, Klaus Rajewsky, and Tomohiro Kurosaki
J. Exp. Med. 2009 206: 681-689. Published online Mar 9 2009, 10.1084/jem.20082100. [Abstract] [Full Text] [PDF (3212K)] [PDF+supp data (5004K)] [Supplemental Material Index]

Syndecan-1 regulates ${alpha}$ _vβ₃ and ${alpha}$ _vβ₅ integrin activation during angiogenesis and is blocked by synstatin, a novel peptide inhibitor

DeannaLee M. Beauvais, Brian J. Ell, Andrea R. McWhorter, and Alan C. Rapraeger
J. Exp. Med. 2009 206: 691-705. Published online Mar 2 2009, 10.1084/jem.20081278. [Abstract] [Full Text] [PDF (7779K)] [Related biobytes podcast]

Cytosolic PLA₂ is required for CTL-mediated immunopathology of celiac disease via NKG2D and IL-15

Fangming Tang, Zhangguo Chen, Cezary Ciszewski, Mala Setty, Jason Solus, Maria Tretiakova, Ellen Ebert, Jin Han, Anning Lin, Stefano Guandalini, Veronika Groh, Thomas Spies, Peter Green, and Bana Jabri
J. Exp. Med. 2009 206: 707-719. Published online Feb 23 2009, 10.1084/jem.20071887. [Abstract] [Full Text] [PDF (3684K)] [PDF+supp data (6570K)] [Supplemental Material Index]

CORRECTIONS:

CD4⁺ regulatory T cells require CTLA-4 for the maintenance of systemic tolerance

Randall H. Friedline, David S. Brown, Hai Nguyen, Hardy Kornfeld, JinHee Lee, Yi Zhang, Mark Appleby, Sandy D. Der, Joonsoo Kang, and Cynthia A. Chambers
J. Exp. Med. 2009 206: 721. Published online Feb 16 2009, 10.1084/jem.2008181120409c. [Full Text] [PDF (415K)]

New twist on the regulation of NKG2D ligand expression

Adelheid Cerwenka
J. Exp. Med. 2009 206: 723. Published online Mar 2 2009, 10.1084/jem.2009022521809c. [Full Text] [PDF (414K)]

FROM THE JCB:

Identification of cell cycle–arrested quiescent osteoclast precursors in vivo

Toshihide Mizoguchi, Akinori Muto, Nobuyuki Udagawa, Atsushi Arai, Teruhito Yamashita, Akihiro Hosoya, Tadashi Ninomiya, Hiroaki Nakamura, Yohei Yamamoto, Saya Kinugawa, Midori Nakamura, Yuko Nakamichi, Yasuhiro Kobayashi, Sakae Nagasawa, Kimimitsu Oda, Hirofumi Tanaka, Mitsuo Tagaya, Josef M. Penninger, Michio Ito, and Naoyuki Takahashi [Full Text]

To see an article, click its [Full Text] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.