JEM -- Table of Contents (206 [10])

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Browse Issues:

Sep 28 2009; 206 (10)

       IN THIS ISSUE

       PEOPLE & IDEAS

       MEETING REVIEW

       BRIEF DEFINITIVE REPORTS

       ARTICLES

       CORRECTIONS

       FROM THE JCB

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To see an article, click its [Full Text] or [PDF] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.
[Index by Author]

PODCAST:

September 21, 2009 The regular packing of lens fiber cells is maintained by Tropomodulin 1 and the spectrin-actin network; IL-9 promiscuity and T helper cell plasticity; TOR-mediated autophagy regulates cell death in Drosophila neurodegenerative disease

IN THIS ISSUE:

IN THIS ISSUE [PDF]

PPAR ${gamma}$ tackles treacherous T cells [Full Text]

EBV takes a toll [Full Text]

Suspected asthma mutation leaves mice gasping [Full Text]

Clingy bacteria and Crohn's disease [Full Text]

"Killer" pathway not guilty [Full Text]

PEOPLE & IDEAS:

Mickie Bhatia: Embryonic stem cells come of age

Amy Maxmen
J. Exp. Med. 2009 206: 2056-2057. Published online Sep 28 2009, 10.1084/jem.20610pi. [Full Text] [PDF (612K)]

MEETING REVIEW:

Regulation of pathogenesis and immunity in helminth infections

Rick M. Maizels, Edward J. Pearce, David Artis, Maria Yazdanbakhsh, and Thomas A. Wynn
J. Exp. Med. 2009 206: 2059-2066. Published online Sep 21 2009, 10.1084/jem.20091903. [Abstract] [Full Text] [PDF (2203K)]

BRIEF DEFINITIVE REPORTS:

Loss of SOCS3 expression in T cells reveals a regulatory role for interleukin-17 in atherosclerosis

Soraya Taleb, Mélissa Romain, Bhama Ramkhelawon, Catherine Uyttenhove, Gerard Pasterkamp, Olivier Herbin, Bruno Esposito, Nicolas Perez, Hideo Yasukawa, Jacques Van Snick, Akihiko Yoshimura, Alain Tedgui, and Ziad Mallat
J. Exp. Med. 2009 206: 2067-2077. Published online Sep 8 2009, 10.1084/jem.20090545. [Abstract] [Full Text] [PDF (4840K)] [PDF+supp data (6616K)] [Supplemental Material]

The nuclear receptor PPAR ${gamma}$ selectively inhibits Th17 differentiation in a T cell–intrinsic fashion and suppresses CNS autoimmunity

Luisa Klotz, Sven Burgdorf, Indra Dani, Kaoru Saijo, Juliane Flossdorf, Stephanie Hucke, Judith Alferink, Natalija Novak, Marc Beyer, Gunter Mayer, Birgit Langhans, Thomas Klockgether, Ari Waisman, Gerard Eberl, Joachim Schultze, Michael Famulok, Waldemar Kolanus, Christopher Glass, Christian Kurts, and Percy A. Knolle
J. Exp. Med. 2009 206: 2079-2089. Published online Sep 8 2009, 10.1084/jem.20082771. [Abstract] [Full Text] [PDF (4351K)] [PDF+supp data (5408K)] [Supplemental Materials]

Epstein-Barr virus (EBV)–encoded small RNA is released from EBV-infected cells and activates signaling from toll-like receptor 3

Dai Iwakiri, Li Zhou, Mrinal Samanta, Misako Matsumoto, Takashi Ebihara, Tsukasa Seya, Shosuke Imai, Mikiya Fujieda, Keisei Kawa, and Kenzo Takada
J. Exp. Med. 2009 206: 2091-2099. Published online Aug 31 2009, 10.1084/jem.20081761. [Abstract] [Full Text] [PDF (3774K)]

NOD2 regulates hematopoietic cell function during graft-versus-host disease

Olaf Penack, Odette M. Smith, Amy Cunningham-Bussel, Xin Liu, Uttam Rao, Nury Yim, Il-Kang Na, Amanda M. Holland, Arnab Ghosh, Sydney X. Lu, Robert R. Jenq, Chen Liu, George F. Murphy, Katharina Brandl, and Marcel R.M. van den Brink
J. Exp. Med. 2009 206: 2101-2110. Published online Sep 8 2009, 10.1084/jem.20090623. [Abstract] [Full Text] [PDF (5315K)] [PDF+supp data (7249K)] [Supplemental Material]

TSLP and IL-7 use two different mechanisms to regulate human CD4⁺ T cell homeostasis

Ning Lu, Yi-Hong Wang, Yui-Hsi Wang, Kazuhiko Arima, Shino Hanabuchi, and Yong-Jun Liu
J. Exp. Med. 2009 206: 2111-2119. Published online Sep 21 2009, 10.1084/jem.20090153. [Abstract] [Full Text] [PDF (5311K)] [PDF+supp data (5826K)] [Supplemental Material]

TCR-dependent differentiation of thymic Foxp3⁺ cells is limited to small clonal sizes

Monica W.L. Leung, Shiqian Shen, and Juan J. Lafaille
J. Exp. Med. 2009 206: 2121-2130. Published online Sep 8 2009, 10.1084/jem.20091033. [Abstract] [Full Text] [PDF (3817K)] [PDF+supp data (6752K)] [Supplemental Material]

Retinoic acid can enhance conversion of naive into regulatory T cells independently of secreted cytokines

Jens Nolting, Carolin Daniel, Sabine Reuter, Christina Stuelten, Peng Li, Henry Sucov, Byung-Gyu Kim, John J. Letterio, Karsten Kretschmer, Hye-Jung Kim, and Harald von Boehmer
J. Exp. Med. 2009 206: 2131-2139. Published online Sep 8 2009, 10.1084/jem.20090639. [Abstract] [Full Text] [PDF (4348K)] [PDF+supp data (8095K)] [Supplemental Material]

GM-CSF regulates intimal cell proliferation in nascent atherosclerotic lesions

Su-Ning Zhu, Mian Chen, Jenny Jongstra-Bilen, and Myron I. Cybulsky
J. Exp. Med. 2009 206: 2141-2149. Published online Sep 14 2009, 10.1084/jem.20090866. [Abstract] [Full Text] [PDF (4495K)] [PDF+supp data (11412K)] [Supplemental Material]

XBP1 governs late events in plasma cell differentiation and is not required for antigen-specific memory B cell development

Derrick J. Todd, Louise J. McHeyzer-Williams, Czeslawa Kowal, Ann-Hwee Lee, Bruce T. Volpe, Betty Diamond, Michael G. McHeyzer-Williams, and Laurie H. Glimcher
J. Exp. Med. 2009 206: 2151-2159. Published online Sep 14 2009, 10.1084/jem.20090738. [Abstract] [Full Text] [PDF (2555K)] [PDF+supp data (3976K)] [Supplemental Material]

ARTICLES:

Caspase-8 deficiency in epidermal keratinocytes triggers an inflammatory skin disease

Andrew Kovalenko, Jin-Chul Kim, Tae-Bong Kang, Akhil Rajput, Konstantin Bogdanov, Oliver Dittrich-Breiholz, Michael Kracht, Ori Brenner, and David Wallach
J. Exp. Med. 2009 206: 2161-2177. Published online Aug 31 2009, 10.1084/jem.20090616. [Abstract] [Full Text] [PDF (9770K)] [PDF+supp data (11388K)] [Supplemental Material]

Crohn's disease adherent-invasive Escherichia coli colonize and induce strong gut inflammation in transgenic mice expressing human CEACAM

Frédéric A. Carvalho, Nicolas Barnich, Adeline Sivignon, Claude Darcha, Carlos H.F. Chan, Clifford P. Stanners, and Arlette Darfeuille-Michaud
J. Exp. Med. 2009 206: 2179-2189. Published online Sep 8 2009, 10.1084/jem.20090741. [Abstract] [Full Text] [PDF (2009K)] [PDF+supp data (2448K)] [Supplemental Material]

Pathogenicity of a disease-associated human IL-4 receptor allele in experimental asthma

Raffi Tachdjian, Clinton Mathias, Shadi Al Khatib, Paul J. Bryce, Hong S. Kim, Frank Blaeser, Brian D. O'Connor, Danuta Rzymkiewicz, Andrew Chen, Michael J. Holtzman, Gurjit K. Hershey, Holger Garn, Hani Harb, Harald Renz, Hans C. Oettgen, and Talal A. Chatila
J. Exp. Med. 2009 206: 2191-2204. Published online Sep 21 2009, 10.1084/jem.20091480. [Abstract] [Full Text] [PDF (3077K)] [PDF+supp data (4308K)] [Supplemental Material]

A murine DC-SIGN homologue contributes to early host defense against Mycobacterium tuberculosis

Antoine Tanne, Bo Ma, Frédéric Boudou, Ludovic Tailleux, Hélène Botella, Edgar Badell, Florence Levillain, Maureen E. Taylor, Kurt Drickamer, Jérome Nigou, Karen M. Dobos, Germain Puzo, Dietmar Vestweber, Martin K. Wild, Marie Marcinko, Peter Sobieszczuk, Lauren Stewart, Daniel Lebus, Brigitte Gicquel, and Olivier Neyrolles
J. Exp. Med. 2009 206: 2205-2220. Published online Sep 21 2009, 10.1084/jem.20090188. [Abstract] [Full Text] [PDF (5645K)] [PDF+supp data (9284K)] [Supplemental Material]

The angiopietin-1–Tie2 pathway prevents rather than promotes pulmonary arterial hypertension in transgenic mice

Lakshmi Kugathasan, Julie Basu Ray, Yupu Deng, Effat Rezaei, Daniel J. Dumont, and Duncan J. Stewart
J. Exp. Med. 2009 206: 2221-2234. Published online Sep 8 2009, 10.1084/jem.20090389. [Abstract] [Full Text] [PDF (4109K)] [PDF+supp data (6266K)] [Supplemental Material]

Activating receptors promote NK cell expansion for maintenance, IL-10 production, and CD8 T cell regulation during viral infection

Seung-Hwan Lee, Kwang-Sin Kim, Nassima Fodil-Cornu, Silvia M. Vidal, and Christine A. Biron
J. Exp. Med. 2009 206: 2235-2251. Published online Aug 31 2009, 10.1084/jem.20082387. [Abstract] [Full Text] [PDF (7091K)] [PDF+supp data (7540K)] [Supplemental Material]

Self–class I MHC molecules support survival of naive CD8 T cells, but depress their functional sensitivity through regulation of CD8 expression levels

Kensuke Takada and Stephen C. Jameson
J. Exp. Med. 2009 206: 2253-2269. Published online Sep 14 2009, 10.1084/jem.20082553. [Abstract] [Full Text] [PDF (3438K)] [PDF+supp data (5687K)] [ Supplemental Material]

Distinct roles for E12 and E47 in B cell specification and the sequential rearrangement of immunoglobulin light chain loci

Kristina Beck, Mandy M. Peak, Takayuki Ota, David Nemazee, and Cornelis Murre
J. Exp. Med. 2009 206: 2271-2284. Published online Sep 14 2009, 10.1084/jem.20090756. [Abstract] [Full Text] [PDF (5292K)] [PDF+supp data (7786K)] [Supplemental Material]

Nonaminoglycoside compounds induce readthrough of nonsense mutations

Liutao Du, Robert Damoiseaux, Shareef Nahas, Kun Gao, Hailiang Hu, Julianne M. Pollard, Jimena Goldstine, Michael E. Jung, Susanne M. Henning, Carmen Bertoni, and Richard A. Gatti
J. Exp. Med. 2009 206: 2285-2297. Published online Sep 21 2009, 10.1084/jem.20081940. [Abstract] [Full Text] [PDF (5782K)] [PDF+supp data (7702K)] [Supplemental Material]

CORRECTIONS:

Blood leukocyte microarrays to diagnose systemic onset juvenile idiopathic arthritis and follow the response to IL-1 blockade

Florence Allantaz, Damien Chaussabel, Dorothee Stichweh, Lynda Bennett, Windy Allman, Asuncion Mejias, Monica Ardura, Wendy Chung, Elisabeth Smith, Carol Wise, Karolina Palucka, Octavio Ramilo, Marilynn Punaro, Jacques Banchereau, and Virginia Pascual
J. Exp. Med. 2009 206: 2299. Published online Sep 14 2009, 10.1084/jem.200700709109c. [Full Text] [PDF (796K)]

Disordered macrophage cytokine secretion underlies impaired acute inflammation and bacterial clearance in Crohn's disease

Andrew M. Smith, Farooq Z. Rahman, Bu'Hussain Hayee, Simon J. Graham, Daniel J.B. Marks, Gavin W. Sewell, Christine D. Palmer, Jonathan Wilde, Brian M.J. Foxwell, Israel S. Gloger, Trevor Sweeting, Mark Marsh, Ann P. Walker, Stuart L. Bloom, and Anthony W. Segal
J. Exp. Med. 2009 206: 2301. Published online Sep 14 2009, 10.1084/jem.20091233090209c. [Full Text] [PDF (791K)]

FROM THE JCB:

Interplay of Oct4 with Sox2 and Sox17: a molecular switch from stem cell pluripotency to specifying a cardiac fate

Sonia Stefanovic, Nesrine Abboud, Stéphanie Désilets, David Nury, Chad Cowan, and Michel Pucéat [Full Text]

TOR-mediated autophagy regulates cell death in Drosophila neurodegenerative disease

Tao Wang, Uyen Lao, and Bruce A. Edgar [Full Text]

The TRC8 E3 ligase ubiquitinates MHC class I molecules before dislocation from the ER

Helen R. Stagg, Mair Thomas, Dick van den Boomen, Emmanuel J.H.J. Wiertz, Harry A. Drabkin, Robert M. Gemmill, and Paul J. Lehner [Full Text]

The dynamin-related GTPase Drp1 is required for embryonic and brain development in mice

Junko Wakabayashi, Zhongyan Zhang, Nobunao Wakabayashi, Yasushi Tamura, Masahiro Fukaya, Thomas W. Kensler, Miho Iijima, and Hiromi Sesaki [Full Text]

Coordination of membrane events during autophagy by multiple class III PI3-kinase complexes

Anne Simonsen and Sharon A. Tooze [Full Text]

To see an article, click its [Full Text] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.