JEM -- Table of Contents (205 [7])

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Jul 7 2008; 205 (7)

       IN THIS ISSUE

       PEOPLE & IDEAS

       COMMENTARIES

       BRIEF DEFINITIVE REPORTS

       ARTICLES

       FROM THE JCB

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To see an article, click its [Full Text] or [PDF] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.
[Index by Author]

PODCAST:

June 30, 2008

IN THIS ISSUE:

IN THIS ISSUE [PDF]

STIM1 strengthens clotting [Full Text]

Timing tolerance to cancer [Full Text]

Why less is worse for lupus [Full Text]

Tumor suppressor fends off lung fibrosis [Full Text]

Two paths lead to MS [Full Text]

PEOPLE & IDEAS:

Jane Skok: Choreography of allelic exclusion

Hema Bashyam
J. Exp. Med. 2008 205: 1514-1515. Published online Jul 7 2008, 10.1084/jem.2057pi. [Full Text] [PDF]

COMMENTARIES:

A rush to judgment on Th17

Lawrence Steinman
J. Exp. Med. 2008 205: 1517-1522. Published online Jun 30 2008, 10.1084/jem.20072066. [Abstract] [Full Text] [PDF]

Differential recognition of double-stranded RNA by RIG-I–like receptors in antiviral immunity

Takeshi Saito and Michael Gale, Jr.
J. Exp. Med. 2008 205: 1523-1527. Published online Jun 30 2008, 10.1084/jem.20081210. [Abstract] [Full Text] [PDF]

Polymers and inflammation: disease mechanisms of the serpinopathies

Bibek Gooptu and David A. Lomas
J. Exp. Med. 2008 205: 1529-1534. Published online Jun 30 2008, 10.1084/jem.20072080. [Abstract] [Full Text] [PDF]

BRIEF DEFINITIVE REPORTS:

IL-12– and IL-23–modulated T cells induce distinct types of EAE based on histology, CNS chemokine profile, and response to cytokine inhibition

Mark A. Kroenke, Thaddeus J. Carlson, Anuska V. Andjelkovic, and Benjamin M. Segal
J. Exp. Med. 2008 205: 1535-1541. Published online Jun 23 2008, 10.1084/jem.20080159. [Abstract] [Full Text] [PDF] [Supplemental Material Index]

Mutations in STAT3 and IL12RB1 impair the development of human IL-17–producing T cells

Ludovic de Beaucoudrey, Anne Puel, Orchidée Filipe-Santos, Aurélie Cobat, Pegah Ghandil, Maya Chrabieh, Jacqueline Feinberg, Horst von Bernuth, Arina Samarina, Lucile Jannière, Claire Fieschi, Jean-Louis Stéphan, Catherine Boileau, Stanislas Lyonnet, Guillaume Jondeau, Valérie Cormier-Daire, Martine Le Merrer, Cyrille Hoarau, Yvon Lebranchu, Olivier Lortholary, Marie-Olivia Chandesris, François Tron, Eleonora Gambineri, Lucia Bianchi, Carlos Rodriguez-Gallego, Simona E. Zitnik, Julia Vasconcelos, Margarida Guedes, Artur Bonito Vitor, Laszlo Marodi, Helen Chapel, Brenda Reid, Chaim Roifman, David Nadal, Janine Reichenbach, Isabel Caragol, Ben-Zion Garty, Figen Dogu, Yildiz Camcioglu, Sanyie Gülle, Ozden Sanal, Alain Fischer, Laurent Abel, Birgitta Stockinger, Capucine Picard, and Jean-Laurent Casanova
J. Exp. Med. 2008 205: 1543-1550. Published online Jun 30 2008, 10.1084/jem.20080321. [Abstract] [Full Text] [PDF] [Supplemental Material Index]

Deficiency of Th17 cells in hyper IgE syndrome due to mutations in STAT3

Cindy S. Ma, Gary Y.J. Chew, Nicholas Simpson, Archana Priyadarshi, Melanie Wong, Bodo Grimbacher, David A. Fulcher, Stuart G. Tangye, and Matthew C. Cook
J. Exp. Med. 2008 205: 1551-1557. Published online Jun 30 2008, 10.1084/jem.20080218. [Abstract] [Full Text] [PDF]

Foxp3⁺ regulatory T cells maintain immune homeostasis in the skin

Jan C. Dudda, Nikole Perdue, Eva Bachtanian, and Daniel J. Campbell
J. Exp. Med. 2008 205: 1559-1565. Published online Jun 23 2008, 10.1084/jem.20072594. [Abstract] [Full Text] [PDF] [Supplemental Material Index]

S ${gamma}$ 3 switch sequences function in place of endogenous S ${gamma}$ 1 to mediate antibody class switching

Ali A. Zarrin, Peter H. Goff, Kate Senger, and Frederick W. Alt
J. Exp. Med. 2008 205: 1567-1572. Published online Jun 9 2008, 10.1084/jem.20080451. [Abstract] [Full Text] [PDF] [Supplemental Material Index]

Copy number of FCGR3B, which is associated with systemic lupus erythematosus, correlates with protein expression and immune complex uptake

Lisa C. Willcocks, Paul A. Lyons, Menna R. Clatworthy, James I. Robinson, Wanling Yang, Stephen A. Newland, Vincent Plagnol, Naomi N. McGovern, Alison M. Condliffe, Edwin R. Chilvers, Dwomoa Adu, Elaine C. Jolly, Richard Watts, Yu Lung Lau, Ann W. Morgan, Gerard Nash, and Kenneth G.C. Smith
J. Exp. Med. 2008 205: 1573-1582. Published online Jun 16 2008, 10.1084/jem.20072413. [Abstract] [Full Text] [PDF] [Supplemental Material Index][Related biobytes podcast]

The calcium sensor STIM1 is an essential mediator of arterial thrombosis and ischemic brain infarction

David Varga-Szabo, Attila Braun, Christoph Kleinschnitz, Markus Bender, Irina Pleines, Mirko Pham, Thomas Renné, Guido Stoll, and Bernhard Nieswandt
J. Exp. Med. 2008 205: 1583-1591. Published online Jun 16 2008, 10.1084/jem.20080302. [Abstract] [Full Text] [PDF] [Supplemental Material Index]

CNI-1493 inhibits Aβ production, plaque formation, and cognitive deterioration in an animal model of Alzheimer's disease

Michael Bacher, Richard Dodel, Bayan Aljabari, Kathy Keyvani, Philippe Marambaud, Rakez Kayed, Charles Glabe, Nicole Goertz, Anne Hoppmann, Norbert Sachser, Jens Klotsche, Susanne Schnell, Lars Lewejohann, and Yousef Al-Abed
J. Exp. Med. 2008 205: 1593-1599. Published online Jun 23 2008, 10.1084/jem.20060467. [Abstract] [Full Text] [PDF] [Supplemental Material Index]

ARTICLES:

Length-dependent recognition of double-stranded ribonucleic acids by retinoic acid–inducible gene-I and melanoma differentiation–associated gene 5

Hiroki Kato, Osamu Takeuchi, Eriko Mikamo-Satoh, Reiko Hirai, Tomoji Kawai, Kazufumi Matsushita, Akane Hiiragi, Terence S. Dermody, Takashi Fujita, and Shizuo Akira
J. Exp. Med. 2008 205: 1601-1610. Published online Jun 30 2008, 10.1084/jem.20080091. [Abstract] [Full Text] [PDF] [Supplemental Material Index]

TAK1 is required for the survival of hematopoietic cells and hepatocytes in mice

Minghui Tang, Xudong Wei, Yinshi Guo, Peter Breslin, Shubin Zhang, Shanshan Zhang, Wei Wei, Zhenbiao Xia, Manuel Diaz, Shizuo Akira, and Jiwang Zhang
J. Exp. Med. 2008 205: 1611-1619. Published online Jun 23 2008, 10.1084/jem.20080297. [Abstract] [Full Text] [PDF] [Supplemental Material Index]

Clearance of influenza virus from the lung depends on migratory langerin⁺CD11b^– but not plasmacytoid dendritic cells

Corine H. GeurtsvanKessel, Monique A.M. Willart, Leonie S. van Rijt, Femke Muskens, Mirjam Kool, Chantal Baas, Kris Thielemans, Clare Bennett, Björn E. Clausen, Henk C. Hoogsteden, Albert D.M.E. Osterhaus, Guus F. Rimmelzwaan, and Bart N. Lambrecht
J. Exp. Med. 2008 205: 1621-1634. Published online Jun 30 2008, 10.1084/jem.20071365. [Abstract] [Full Text] [PDF] [Supplemental Material Index]

Protective influenza-specific CD8 T cell responses require interactions with dendritic cells in the lungs

Jodi McGill, Nico Van Rooijen, and Kevin L. Legge
J. Exp. Med. 2008 205: 1635-1646. Published online Jun 30 2008, 10.1084/jem.20080314. [Abstract] [Full Text] [PDF] [Supplemental Material Index]

An MHC class Ib–restricted CD8 T cell response confers antiviral immunity

Phillip A. Swanson, II, Christopher D. Pack, Annette Hadley, Chyung-Ru Wang, Iwona Stroynowski, Peter E. Jensen, and Aron E. Lukacher
J. Exp. Med. 2008 205: 1647-1657. Published online Jun 9 2008, 10.1084/jem.20080570. [Abstract] [Full Text] [PDF]

Pathological integrin signaling enhances proliferation of primary lung fibroblasts from patients with idiopathic pulmonary fibrosis

Hong Xia, Deanna Diebold, Richard Nho, David Perlman, Jill Kleidon, Judy Kahm, Svetlana Avdulov, Mark Peterson, John Nerva, Peter Bitterman, and Craig Henke
J. Exp. Med. 2008 205: 1659-1672. Published online Jun 9 2008, 10.1084/jem.20080001. [Abstract] [Full Text] [PDF]

Tumor angiogenesis and progression are enhanced by Sema4D produced by tumor-associated macrophages

Jose Rafael Sierra, Simona Corso, Luisa Caione, Virna Cepero, Paolo Conrotto, Alessandro Cignetti, Wanda Piacibello, Atsushi Kumanogoh, Hitoshi Kikutani, Paolo Maria Comoglio, Luca Tamagnone, and Silvia Giordano
J. Exp. Med. 2008 205: 1673-1685. Published online Jun 16 2008, 10.1084/jem.20072602. [Abstract] [Full Text] [PDF] [Supplemental Material Index]

Immunogenicity of premalignant lesions is the primary cause of general cytotoxic T lymphocyte unresponsiveness

Gerald Willimsky, Melinda Czéh, Christoph Loddenkemper, Johanna Gellermann, Karin Schmidt, Peter Wust, Harald Stein, and Thomas Blankenstein
J. Exp. Med. 2008 205: 1687-1700. Published online Jun 23 2008, 10.1084/jem.20072016. [Abstract] [Full Text] [PDF] [Supplemental Material Index]

Administration of rhIL-7 in humans increases in vivo TCR repertoire diversity by preferential expansion of naive T cell subsets

Claude Sportès, Frances T. Hakim, Sarfraz A. Memon, Hua Zhang, Kevin S. Chua, Margaret R. Brown, Thomas A. Fleisher, Michael C. Krumlauf, Rebecca R. Babb, Catherine K. Chow, Terry J. Fry, Julie Engels, Renaud Buffet, Michel Morre, Robert J. Amato, David J. Venzon, Robert Korngold, Andrew Pecora, Ronald E. Gress, and Crystal L. Mackall
J. Exp. Med. 2008 205: 1701-1714. Published online Jun 23 2008, 10.1084/jem.20071681. [Abstract] [Full Text] [PDF] [Supplemental Material Index]

FROM THE JCB:

Cytokine secretion requires phosphatidylcholine synthesis

Yong Tian, Caroline Pate, Alberto Andreolotti, Limin Wang, Elaine Tuomanen, Kelli Boyd, Enrique Claro, and Suzanne Jackowski [Full Text]

To see an article, click its [Full Text] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.