JEM -- Table of Contents (205 [12])

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Nov 24 2008; 205 (12)

       IN THIS ISSUE

       PEOPLE & IDEAS

       COMMENTARIES

       BRIEF DEFINITIVE REPORTS

       ARTICLES

       FROM THE JCB

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To see an article, click its [Full Text] or [PDF] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.
[Index by Author]

PODCAST:

November 17, 2008

IN THIS ISSUE:

IN THIS ISSUE [PDF]

Adenovirus antibodies assist HIV [Full Text]

Acid to remember [Full Text]

Epithelial cells as APCs [Full Text]

Beekeepers show way to allergen tolerance [Full Text]

Reviving the attack against HIV [Full Text]

PEOPLE & IDEAS:

Andrea Cooper: Using pathogens to probe the immune response

Kira O'Day
J. Exp. Med. 2008 205: 2690-2691. Published online Nov 24 2008, 10.1084/jem.20512pi. [Full Text] [PDF (813K)]

COMMENTARIES:

Out of breath: GM-CSFR ${alpha}$ mutations disrupt surfactant homeostasis

Luigi D. Notarangelo and Itai Pessach
J. Exp. Med. 2008 205: 2693-2697. Published online Nov 17 2008, 10.1084/jem.20082378. [Abstract] [Full Text] [PDF (1059K)]

TIMs: central regulators of immune responses

David A. Hafler and Vijay Kuchroo
J. Exp. Med. 2008 205: 2699-2701. Published online Nov 17 2008, 10.1084/jem.20082429. [Abstract] [Full Text] [PDF (698K)]

BRIEF DEFINITIVE REPORTS:

Familial pulmonary alveolar proteinosis caused by mutations in CSF2RA

Takuji Suzuki, Takuro Sakagami, Bruce K. Rubin, Lawrence M. Nogee, Robert E. Wood, Sarah L. Zimmerman, Teresa Smolarek, Megan K. Dishop, Susan E. Wert, Jeffrey A. Whitsett, Gregory Grabowski, Brenna C. Carey, Carrie Stevens, Johannes C.M. van der Loo, and Bruce C. Trapnell
J. Exp. Med. 2008 205: 2703-2710. Published online Oct 27 2008, 10.1084/jem.20080990. [Abstract] [Full Text] [PDF (2813K)] [Supplemental Material Index]

Pulmonary alveolar proteinosis caused by deletion of the GM-CSFR ${alpha}$ gene in the X chromosome pseudoautosomal region 1

Margarita Martinez-Moczygemba, Minh L. Doan, Okan Elidemir, Leland L. Fan, Sau Wai Cheung, Jonathan T. Lei, James P. Moore, Ghamartaj Tavana, Lora R. Lewis, Yiming Zhu, Donna M. Muzny, Richard A. Gibbs, and David P. Huston
J. Exp. Med. 2008 205: 2711-2716. Published online Oct 27 2008, 10.1084/jem.20080759. [Abstract] [Full Text] [PDF (1832K)] [Supplemental Material Index]

Activation of a dendritic cell–T cell axis by Ad5 immune complexes creates an improved environment for replication of HIV in T cells

Matthieu Perreau, Giuseppe Pantaleo, and Eric J. Kremer
J. Exp. Med. 2008 205: 2717-2725. Published online Nov 3 2008, 10.1084/jem.20081786. [Abstract] [Full Text] [PDF (3083K)] [Supplemental Material Index]

A novel subset of mouse NKT cells bearing the IL-17 receptor B responds to IL-25 and contributes to airway hyperreactivity

Asuka Terashima, Hiroshi Watarai, Sayo Inoue, Etsuko Sekine, Ryusuke Nakagawa, Koji Hase, Chiaki Iwamura, Hiroshi Nakajima, Toshinori Nakayama, and Masaru Taniguchi
J. Exp. Med. 2008 205: 2727-2733. Published online Nov 17 2008, 10.1084/jem.20080698. [Abstract] [Full Text] [PDF (1998K)] [Supplemental Material Index]

T cell receptor contact to restricting MHC molecules is a prerequisite for peripheral interclonal T cell competition

Fabien Agenès, Jean-Pierre Dangy, and Jörg Kirberg
J. Exp. Med. 2008 205: 2735-2743. Published online Nov 17 2008, 10.1084/jem.20070467. [Abstract] [Full Text] [PDF (2229K)] [Supplemental Material Index]

Altered kinetics of nonhomologous end joining and class switch recombination in ligase IV–deficient B cells

Li Han and Kefei Yu
J. Exp. Med. 2008 205: 2745-2753. Published online Nov 10 2008, 10.1084/jem.20081623. [Abstract] [Full Text] [PDF (5369K)]

B cells drive lymphocyte activation and expansion in mice with the CD45 wedge mutation and Fas deficiency

Vikas A. Gupta, Michelle L. Hermiston, Gail Cassafer, David I. Daikh, and Arthur Weiss
J. Exp. Med. 2008 205: 2755-2761. Published online Nov 10 2008, 10.1084/jem.20081204. [Abstract] [Full Text] [PDF (3030K)] [Supplemental Material Index]

ARTICLES:

Tim-3 expression defines a novel population of dysfunctional T cells with highly elevated frequencies in progressive HIV-1 infection

R. Brad Jones, Lishomwa C. Ndhlovu, Jason D. Barbour, Prameet M. Sheth, Aashish R. Jha, Brian R. Long, Jessica C. Wong, Malathy Satkunarajah, Marc Schweneker, Joan M. Chapman, Gabor Gyenes, Bahareh Vali, Martin D. Hyrcza, Feng Yun Yue, Colin Kovacs, Aref Sassi, Mona Loutfy, Roberta Halpenny, Desmond Persad, Gerald Spotts, Frederick M. Hecht, Tae-Wook Chun, Joseph M. McCune, Rupert Kaul, James M. Rini, Douglas F. Nixon, and Mario A. Ostrowski
J. Exp. Med. 2008 205: 2763-2779. Published online Nov 10 2008, 10.1084/jem.20081398. [Abstract] [Full Text] [PDF (10720K)] [Supplemental Material Index]

Valproic acid inhibits Aβ production, neuritic plaque formation, and behavioral deficits in Alzheimer's disease mouse models

Hong Qing, Guiqiong He, Philip T. T. Ly, Christopher J. Fox, Matthias Staufenbiel, Fang Cai, Zhuohua Zhang, Shengcai Wei, Xiulian Sun, Chia-Hsiung Chen, Weihui Zhou, Ke Wang, and Weihong Song
J. Exp. Med. 2008 205: 2781-2789. Published online Oct 27 2008, 10.1084/jem.20081588. [Abstract] [Full Text] [PDF (2434K)] [Supplemental Material Index][Related biobytes podcast]

Lipid mediators in innate immunity against tuberculosis: opposing roles of PGE₂ and LXA₄ in the induction of macrophage death

Minjian Chen, Maziar Divangahi, Huixian Gan, Daniel S.J. Shin, Song Hong, David M. Lee, Charles N. Serhan, Samuel M. Behar, and Heinz G. Remold
J. Exp. Med. 2008 205: 2791-2801. Published online Oct 27 2008, 10.1084/jem.20080767. [Abstract] [Full Text] [PDF (1645K)] [Supplemental Material Index]

Tpl2 kinase regulates T cell interferon- ${gamma}$ production and host resistance to Toxoplasma gondii

Wendy T. Watford, Bruce D. Hissong, Lydia R. Durant, Hidehiro Yamane, Linda M. Muul, Yuka Kanno, Cristina M. Tato, Haydeé L. Ramos, Alan E. Berger, Lisa Mielke, Marko Pesu, Benjamin Solomon, David M. Frucht, William E. Paul, Alan Sher, Dragana Jankovic, Philip N. Tsichlis, and John J. O'Shea
J. Exp. Med. 2008 205: 2803-2812. Published online Nov 10 2008, 10.1084/jem.20081461. [Abstract] [Full Text] [PDF (2157K)] [Supplemental Material Index]

A novel genetic strategy reveals unexpected roles of the Swi–Snf–like chromatin-remodeling BAF complex in thymocyte development

Anant Jani, Mimi Wan, Jianmin Zhang, Kairong Cui, Jie Wu, Paula Preston-Hurlburt, Rohini Khatri, Keji Zhao, and Tian Chi
J. Exp. Med. 2008 205: 2813-2825. Published online Oct 27 2008, 10.1084/jem.20080938. [Abstract] [Full Text] [PDF (5052K)] [Supplemental Material Index]

Aire controls the differentiation program of thymic epithelial cells in the medulla for the establishment of self-tolerance

Masashi Yano, Noriyuki Kuroda, Hongwei Han, Makiko Meguro-Horike, Yumiko Nishikawa, Hiroshi Kiyonari, Kentaro Maemura, Yuchio Yanagawa, Kunihiko Obata, Satoru Takahashi, Tomokatsu Ikawa, Rumi Satoh, Hiroshi Kawamoto, Yasuhiro Mouri, and Mitsuru Matsumoto
J. Exp. Med. 2008 205: 2827-2838. Published online Nov 17 2008, 10.1084/jem.20080046. [Abstract] [Full Text] [PDF (2596K)] [Supplemental Material Index]

Lymph-migrating, tissue-derived dendritic cells are minor constituents within steady-state lymph nodes

Claudia Jakubzick, Milena Bogunovic, Anthony J. Bonito, Emma L. Kuan, Miriam Merad, and Gwendalyn J. Randolph
J. Exp. Med. 2008 205: 2839-2850. Published online Nov 3 2008, 10.1084/jem.20081430. [Abstract] [Full Text] [PDF (3476K)] [Supplemental Material Index]

Oncogenesis of T-ALL and nonmalignant consequences of overexpressing intracellular NOTCH1

Xiaoyu Li, Fotini Gounari, Alexei Protopopov, Khashayarsha Khazaie, and Harald von Boehmer
J. Exp. Med. 2008 205: 2851-2861. Published online Nov 3 2008, 10.1084/jem.20081561. [Abstract] [Full Text] [PDF (4327K)] [Supplemental Material Index]

Toward targeting B cell cancers with CD4⁺ CTLs: identification of a CD19-encoded minor histocompatibility antigen using a novel genome-wide analysis

Robbert M. Spaapen, Henk M. Lokhorst, Kelly van den Oudenalder, Brith E. Otterud, Harry Dolstra, Mark F. Leppert, Monique C. Minnema, Andries C. Bloem, and Tuna Mutis
J. Exp. Med. 2008 205: 2863-2872. Published online Nov 10 2008, 10.1084/jem.20080713. [Abstract] [Full Text] [PDF (2477K)] [Supplemental Material Index]

ICOS-dependent extrafollicular helper T cells elicit IgG production via IL-21 in systemic autoimmunity

Jared M. Odegard, Benjamin R. Marks, Leah D. DiPlacido, Amanda C. Poholek, Dwight H. Kono, Chen Dong, Richard A. Flavell, and Joe Craft
J. Exp. Med. 2008 205: 2873-2886. Published online Nov 3 2008, 10.1084/jem.20080840. [Abstract] [Full Text] [PDF (5337K)] [Supplemental Material Index]

In vivo switch to IL-10–secreting T regulatory cells in high dose allergen exposure

Flurina Meiler, Judith Zumkehr, Sven Klunker, Beate Rückert, Cezmi A. Akdis, and Mübeccel Akdis
J. Exp. Med. 2008 205: 2887-2898. Published online Nov 10 2008, 10.1084/jem.20080193. [Abstract] [Full Text] [PDF (2732K)] [Supplemental Material Index]

A point mutation in the murine Hem1 gene reveals an essential role for Hematopoietic Protein 1 in lymphopoiesis and innate immunity

Heon Park, Karen Staehling-Hampton, Mark W. Appleby, Mary E. Brunkow, Tania Habib, Yi Zhang, Fred Ramsdell, H. Denny Liggitt, Brian Freie, Mark Tsang, George Carlson, Sherree Friend, Charles Frevert, and Brian M. Iritani
J. Exp. Med. 2008 205: 2899-2913. Published online Nov 17 2008, 10.1084/jem.20080340. [Abstract] [Full Text] [PDF (9473K)] [Supplemental Material Index]

Expression of the retinoblastoma protein RbAp48 in exocrine glands leads to Sjögren's syndrome–like autoimmune exocrinopathy

Naozumi Ishimaru, Rieko Arakaki, Satoko Yoshida, Akiko Yamada, Sumihare Noji, and Yoshio Hayashi
J. Exp. Med. 2008 205: 2915-2927. Published online Nov 17 2008, 10.1084/jem.20080174. [Abstract] [Full Text] [PDF (7499K)] [Supplemental Material Index]

VE-PTP maintains the endothelial barrier via plakoglobin and becomes dissociated from VE-cadherin by leukocytes and by VEGF

Astrid F. Nottebaum, Giuseppe Cagna, Mark Winderlich, Alexander C. Gamp, Ruth Linnepe, Christian Polaschegg, Kristina Filippova, Ruth Lyck, Britta Engelhardt, Olena Kamenyeva, Maria Gabriele Bixel, Stefan Butz, and Dietmar Vestweber
J. Exp. Med. 2008 205: 2929-2945. Published online Nov 17 2008, 10.1084/jem.20080406. [Abstract] [Full Text] [PDF (5944K)] [Supplemental Material Index]

FROM THE JCB:

The BH3-only protein Bik/Blk/Nbk inhibits nuclear translocation of activated ERK1/2 to mediate IFNg-induced cell death

Yohannes A. Mebratu, Burton F. Dickey, Chris Evans, and Yohannes Tesfaigzi [Full Text]

Toll-like receptor 4 restricts retinal progenitor cell proliferation

Ravid Shechter, Ayal Ronen, Asya Rolls, Anat London, Sharon Bakalash, Michael J. Young, and Michal Schwartz [Full Text]

Endothelial adhesion receptors are recruited to adherent leukocytes by inclusion in preformed tetraspanin nanoplatforms

Olga Barreiro, Moreno Zamai, María Yáñez-Mó, Emilio Tejera, Pedro López-Romero, Peter N. Monk, Enrico Gratton, Valeria R. Caiolfa, and Francisco Sánchez-Madrid [Full Text]

To see an article, click its [Full Text] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.