JEM -- Table of Contents (205 [11])

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Oct 27 2008; 205 (11)

       IN THIS ISSUE

       PEOPLE & IDEAS

       BRIEF DEFINITIVE REPORTS

       ARTICLES

       CORRECTIONS

       FROM THE JCB

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To see an article, click its [Full Text] or [PDF] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.
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PODCAST:

October 22, 2008

IN THIS ISSUE:

IN THIS ISSUE [PDF]

Autoimmunity fought in the cortex [Full Text]

Death receptor chews up bone [Full Text]

Pain in the brain [Full Text]

Friend to the brain, foe to the spine [Full Text]

Giving imatinib a hand [Full Text]

PEOPLE & IDEAS:

Nicole Baumgarth: Tackling flu from a B cell angle

Amy Maxmen
J. Exp. Med. 2008 205: 2454-2455. Published online Oct 27 2008, 10.1084/jem.20511pi. [Full Text] [PDF (671K)]

BRIEF DEFINITIVE REPORTS:

The Death Receptor 3–TNF-like protein 1A pathway drives adverse bone pathology in inflammatory arthritis

Melanie Jane Bull, Anwen Siân Williams, Zarabeth Mecklenburgh, Claudia Jane Calder, Jason Peter Twohig, Carole Elford, Bronwen Alice James Evans, Tania F. Rowley, Tomasz J. Slebioda, Vadim Y. Taraban, Aymen Al-Shamkhani, and Eddie Chung Yern Wang
J. Exp. Med. 2008 205: 2457-2464. Published online Sep 29 2008, 10.1084/jem.20072378. [Abstract] [Full Text] [PDF (3273K)]

Human PMS2 deficiency is associated with impaired immunoglobulin class switch recombination

Sophie Péron, Ayse Metin, Pauline Gardès, Marie-Alexandra Alyanakian, Eamonn Sheridan, Christian Peter Kratz, Alain Fischer, and Anne Durandy
J. Exp. Med. 2008 205: 2465-2472. Published online Sep 29 2008, 10.1084/jem.20080789. [Abstract] [Full Text] [PDF (2066K)] [Supplemental Material Index]

Aquaporin-4–binding autoantibodies in patients with neuromyelitis optica impair glutamate transport by down-regulating EAAT2

Shannon R. Hinson, Shanu F. Roemer, Claudia F. Lucchinetti, James P. Fryer, Thomas J. Kryzer, Jayne L. Chamberlain, Charles L. Howe, Sean J. Pittock, and Vanda A. Lennon
J. Exp. Med. 2008 205: 2473-2481. Published online Oct 6 2008, 10.1084/jem.20081241. [Abstract] [Full Text] [PDF (3874K)] [Related biobytes podcast]

Stromal mesenteric lymph node cells are essential for the generation of gut-homing T cells in vivo

Swantje I. Hammerschmidt, Manuela Ahrendt, Ulrike Bode, Benjamin Wahl, Elisabeth Kremmer, Reinhold Förster, and Oliver Pabst
J. Exp. Med. 2008 205: 2483-2490. Published online Oct 13 2008, 10.1084/jem.20080039. [Abstract] [Full Text] [PDF (2194K)] [Supplemental Material Index]

Blockade of tumor necrosis factor in collagen-induced arthritis reveals a novel immunoregulatory pathway for Th1 and Th17 cells

Clare A. Notley, Julia J. Inglis, Saba Alzabin, Fiona E. McCann, Kay E. McNamee, and Richard O. Williams
J. Exp. Med. 2008 205: 2491-2497. Published online Oct 20 2008, 10.1084/jem.20072707. [Abstract] [Full Text] [PDF (1249K)] [Supplemental Material Index]

Myeloid cell differentiation arrest by miR-125b-1 in myelodysplasic syndrome and acute myeloid leukemia with the t(2;11)(p21;q23) translocation

Marina Bousquet, Cathy Quelen, Roberto Rosati, Véronique Mansat-De Mas, Roberta La Starza, Christian Bastard, Eric Lippert, Pascaline Talmant, Marina Lafage-Pochitaloff, Dominique Leroux, Carine Gervais, Franck Viguié, Jean-Luc Lai, Christine Terre, Berna Beverlo, Costantina Sambani, Anne Hagemeijer, Peter Marynen, Georges Delsol, Nicole Dastugue, Cristina Mecucci, and Pierre Brousset
J. Exp. Med. 2008 205: 2499-2506. Published online Oct 20 2008, 10.1084/jem.20080285. [Abstract] [Full Text] [PDF (3760K)] [Supplemental Material Index]

Delta-like 4 is indispensable in thymic environment specific for T cell development

Katsuto Hozumi, Carolina Mailhos, Naoko Negishi, Ken-ichi Hirano, Takashi Yahata, Kiyoshi Ando, Saulius Zuklys, Georg A. Holländer, David T. Shima, and Sonoko Habu
J. Exp. Med. 2008 205: 2507-2513. Published online Sep 29 2008, 10.1084/jem.20080134. [Abstract] [Full Text] [PDF (3608K)] [Supplemental Material Index]

Delta-like 4 is the essential, nonredundant ligand for Notch1 during thymic T cell lineage commitment

Ute Koch, Emma Fiorini, Rui Benedito, Valerie Besseyrias, Karin Schuster-Gossler, Michel Pierres, Nancy R. Manley, Antonio Duarte, H. Robson MacDonald, and Freddy Radtke
J. Exp. Med. 2008 205: 2515-2523. Published online Sep 29 2008, 10.1084/jem.20080829. [Abstract] [Full Text] [PDF (3794K)]

ARTICLES:

Mind bomb 1 in the lymphopoietic niches is essential for T and marginal zone B cell development

Ran Song, Young-Woong Kim, Bon-Kyoung Koo, Hyun-Woo Jeong, Mi-Jeong Yoon, Ki-Jun Yoon, Dong-Jae Jun, Sun-Kyoung Im, Juhee Shin, Myoung-Phil Kong, Kyong-Tai Kim, Keejung Yoon, and Young-Yun Kong
J. Exp. Med. 2008 205: 2525-2536. Published online Sep 29 2008, 10.1084/jem.20081344. [Abstract] [Full Text] [PDF (4245K)] [Supplemental Material Index]

Macaques vaccinated with live-attenuated SIV control replication of heterologous virus

Matthew R. Reynolds, Andrea M. Weiler, Kim L. Weisgrau, Shari M. Piaskowski, Jessica R. Furlott, Jason T. Weinfurter, Masahiko Kaizu, Taeko Soma, Enrique J. León, Caitlin MacNair, Dan P. Leaman, Michael B. Zwick, Emma Gostick, Solomon K. Musani, David A. Price, Thomas C. Friedrich, Eva G. Rakasz, Nancy A. Wilson, Adrian B. McDermott, Rosanne Boyle, David B. Allison, Dennis R. Burton, Wayne C. Koff, and David I. Watkins
J. Exp. Med. 2008 205: 2537-2550. Published online Oct 6 2008, 10.1084/jem.20081524. [Abstract] [Full Text] [PDF (2943K)] [Supplemental Material Index]

An Epstein-Barr virus–encoded microRNA targets PUMA to promote host cell survival

Elizabeth Yee-Wai Choy, Kam-Leung Siu, Kin-Hang Kok, Raymond Wai-Ming Lung, Chi Man Tsang, Ka-Fai To, Dora Lai-Wan Kwong, Sai Wah Tsao, and Dong-Yan Jin
J. Exp. Med. 2008 205: 2551-2560. Published online Oct 6 2008, 10.1084/jem.20072581. [Abstract] [Full Text] [PDF (1499K)] [Supplemental Material Index]

CD40L⁺ CD4⁺ memory T cells migrate in a CD62P-dependent fashion into reactive lymph nodes and license dendritic cells for T cell priming

Alfonso Martín-Fontecha, Dirk Baumjohann, Greta Guarda, Andrea Reboldi, Miroslav Hons, Antonio Lanzavecchia, and Federica Sallusto
J. Exp. Med. 2008 205: 2561-2574. Published online Oct 6 2008, 10.1084/jem.20081212. [Abstract] [Full Text] [PDF (3215K)] [Supplemental Material Index]

Clonal deletion of thymocytes can occur in the cortex with no involvement of the medulla

Tom M. McCaughtry, Troy A. Baldwin, Matthew S. Wilken, and Kristin A. Hogquist
J. Exp. Med. 2008 205: 2575-2584. Published online Oct 20 2008, 10.1084/jem.20080866. [Abstract] [Full Text] [PDF (2168K)] [Supplemental Material Index]

Regulation of class switch recombination and somatic mutation by AID phosphorylation

Kevin M. McBride, Anna Gazumyan, Eileen M. Woo, Tanja A. Schwickert, Brian T. Chait, and Michel C. Nussenzweig
J. Exp. Med. 2008 205: 2585-2594. Published online Oct 6 2008, 10.1084/jem.20081319. [Abstract] [Full Text] [PDF (2934K)] [Supplemental Material Index]

Tuning sensitivity to IL-4 and IL-13: differential expression of IL-4R ${alpha}$ , IL-13R ${alpha}$ 1, and ${gamma}$ c regulates relative cytokine sensitivity

Ilkka S. Junttila, Kiyoshi Mizukami, Harold Dickensheets, Martin Meier-Schellersheim, Hidehiro Yamane, Raymond P. Donnelly, and William E. Paul
J. Exp. Med. 2008 205: 2595-2608. Published online Oct 13 2008, 10.1084/jem.20080452. [Abstract] [Full Text] [PDF (5522K)] [Supplemental Material Index]

TLR3 is an endogenous sensor of tissue necrosis during acute inflammatory events

Karen A. Cavassani, Makoto Ishii, Haitao Wen, Matthew A. Schaller, Pamela M. Lincoln, Nicholas W. Lukacs, Cory M. Hogaboam, and Steven L. Kunkel
J. Exp. Med. 2008 205: 2609-2621. Published online Oct 6 2008, 10.1084/jem.20081370. [Abstract] [Full Text] [PDF (5288K)] [Supplemental Material Index]

Elevated levels of placental growth factor represent an adaptive host response in sepsis

Kiichiro Yano, Yoshiaki Okada, Guido Beldi, Shou-Ching Shih, Natalya Bodyak, Hitomi Okada, Peter M. Kang, William Luscinskas, Simon C. Robson, Peter Carmeliet, S. Ananth Karumanchi, and William C. Aird
J. Exp. Med. 2008 205: 2623-2631. Published online Oct 13 2008, 10.1084/jem.20080398. [Abstract] [Full Text] [PDF (5571K)] [Supplemental Material Index]

Regional CNS responses to IFN- ${gamma}$ determine lesion localization patterns during EAE pathogenesis

Jason R. Lees, Paul T. Golumbek, Julia Sim, Denise Dorsey, and John H. Russell
J. Exp. Med. 2008 205: 2633-2642. Published online Oct 13 2008, 10.1084/jem.20080155. [Abstract] [Full Text] [PDF (993K)] [Supplemental Material Index]

CXCL12 (SDF-1 ${alpha}$ ) suppresses ongoing experimental autoimmune encephalomyelitis by selecting antigen-specific regulatory T cells

Moran Meiron, Yaniv Zohar, Rachel Anunu, Gizi Wildbaum, and Nathan Karin
J. Exp. Med. 2008 205: 2643-2655. Published online Oct 13 2008, 10.1084/jem.20080730. [Abstract] [Full Text] [PDF (3299K)]

AHI-1 interacts with BCR-ABL and modulates BCR-ABL transforming activity and imatinib response of CML stem/progenitor cells

Liang L. Zhou, Yun Zhao, Ashley Ringrose, Donna DeGeer, Erin Kennah, Ann E.-J. Lin, Guoqing Sheng, Xiao-Jiang Li, Ali Turhan, and Xiaoyan Jiang
J. Exp. Med. 2008 205: 2657-2671. Published online Oct 20 2008, 10.1084/jem.20072316. [Abstract] [Full Text] [PDF (2524K)] [Supplemental Material Index]

MELOE-1 is a new antigen overexpressed in melanomas and involved in adoptive T cell transfer efficiency

Yann Godet, Agnès Moreau-Aubry, Yannik Guilloux, Virginie Vignard, Amir Khammari, Brigitte Dreno, Francine Jotereau, and Nathalie Labarriere
J. Exp. Med. 2008 205: 2673-2682. Published online Oct 20 2008, 10.1084/jem.20081356. [Abstract] [Full Text] [PDF (666K)]

CORRECTIONS:

Transient high glucose causes persistent epigenetic changes and altered gene expression during subsequent normoglycemia

Assam El-Osta, Daniella Brasacchio, Dachun Yao, Alessandro Pocai, Peter L. Jones, Robert G. Roeder, Mark E. Cooper, and Michael Brownlee
J. Exp. Med. 2008 205: 2683. Published online Oct 6 2008, 10.1084/jem.20081188092608c. [Full Text] [PDF (408K)]

FROM THE JCB:

Identification of specific histidines as pH sensors in flavivirus membrane fusion

Richard Fritz, Karin Stiasny, and Franz X. Heinz [Full Text]

Notch1 signaling stimulates proliferation of immature cardiomyocytes

Chiara Collesi, Lorena Zentilin, Gianfranco Sinagra, and Mauro Giacca [Full Text]

Notch activates cell cycle reentry and progression in quiescent cardiomyocytes

Víctor M. Campa, Raquel Gutiérrez-Lanza, Fabio Cerignoli, Ramón Díaz-Trelles, Brandon Nelson, Toshiya Tsuji, Maria Barcova, Wei Jiang, and Mark Mercola [Full Text]

To see an article, click its [Full Text] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.