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[Cover Caption] Browse Issues:		Jun 11 2007; 204 (6)        IN THIS ISSUE        FROM THE ARCHIVE        COMMENTARIES        BRIEF DEFINITIVE REPORTS        ARTICLES        FROM THE JCB
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To see an article, click its [Full Text] or [PDF] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.
[Index by Author]

 

IN THIS ISSUE:

IN THIS ISSUE [PDF]

Vessel-widening by VEGF [Full Text]  

RANK brings Aire into the thymus [Full Text]  

cAMP crosses junctions [Full Text]  

Tumor-killing DCs [Full Text]  

Bacterial toxin cripples dendritic cells [Full Text]  

Regulatory T cells carry new ID [Full Text]  

 

FROM THE ARCHIVE:

FROM THE ARCHIVE [PDF]

CTLA-4: From conflict to clinic [Abstract] [Full Text]  

 

COMMENTARIES:

Complement factor H and the hemolytic uremic syndrome

John P. Atkinson and Timothy H.J. Goodship
J. Exp. Med. 2007 204: 1245-1248. Published online Jun 4 2007, 10.1084/jem.20070664. [Abstract] [Full Text] [PDF]  

 

BRIEF DEFINITIVE REPORTS:

Spontaneous hemolytic uremic syndrome triggered by complement factor H lacking surface recognition domains

Matthew C. Pickering, Elena Goicoechea de Jorge, Rubén Martinez-Barricarte, Sergio Recalde, Alfredo Garcia-Layana, Kirsten L. Rose, Jill Moss, Mark J. Walport, H. Terence Cook, Santiago Rodriguez de Córdoba, and Marina Botto
J. Exp. Med. 2007 204: 1249-1256. Published online May 21 2007, 10.1084/jem.20070301. [Abstract] [Full Text] [PDF] [Supplemental Material Index]  

Adenosine generation catalyzed by CD39 and CD73 expressed on regulatory T cells mediates immune suppression

Silvia Deaglio, Karen M. Dwyer, Wenda Gao, David Friedman, Anny Usheva, Anna Erat, Jiang-Fan Chen, Keiichii Enjyoji, Joel Linden, Mohamed Oukka, Vijay K. Kuchroo, Terry B. Strom, and Simon C. Robson
J. Exp. Med. 2007 204: 1257-1265. Published online May 14 2007, 10.1084/jem.20062512. [Abstract] [Full Text] [PDF]  

RANK signals from CD4⁺3^– inducer cells regulate development of Aire-expressing epithelial cells in the thymic medulla

Simona W. Rossi, Mi-Yeon Kim, Andreas Leibbrandt, Sonia M. Parnell, William E. Jenkinson, Stephanie H. Glanville, Fiona M. McConnell, Hamish S. Scott, Josef M. Penninger, Eric J. Jenkinson, Peter J.L. Lane, and Graham Anderson
J. Exp. Med. 2007 204: 1267-1272. Published online May 14 2007, 10.1084/jem.20062497. [Abstract] [Full Text] [PDF]  

G-CSF rescues the memory impairment of animal models of Alzheimer's disease

Kuen-Jer Tsai, Yueh-Chiao Tsai, and Che-Kun James Shen
J. Exp. Med. 2007 204: 1273-1280. Published online May 21 2007, 10.1084/jem.20062481. [Abstract] [Full Text] [PDF]  

Cryoelectron tomography reveals periodic material at the inner side of subpellicular microtubules in apicomplexan parasites

Marek Cyrklaff, Mikhail Kudryashev, Andrew Leis, Kevin Leonard, Wolfgang Baumeister, Robert Menard, Markus Meissner, and Friedrich Frischknecht
J. Exp. Med. 2007 204: 1281-1287. Published online Jun 11 2007, 10.1084/jem.20062405. [Abstract] [Full Text] [PDF] [Supplemental Material Index]  

Th2-driven, allergen-induced airway inflammation is reduced after treatment with anti–Tim-3 antibody in vivo

Jennifer Kearley, Sarah J. McMillan, and Clare M. Lloyd
J. Exp. Med. 2007 204: 1289-1294. Published online May 21 2007, 10.1084/jem.20062093. [Abstract] [Full Text] [PDF] [Supplemental Material Index]  

Tumor suppressor p53 Arg72Pro polymorphism and longevity, cancer survival, and risk of cancer in the general population

David Dynnes Ørsted, Stig Egil Bojesen, Anne Tybjærg-Hansen, and Børge Grønne Nordestgaard
J. Exp. Med. 2007 204: 1295-1301. Published online May 29 2007, 10.1084/jem.20062476. [Abstract] [Full Text] [PDF] [Supplemental Material Index]  

Cyclic adenosine monophosphate is a key component of regulatory T cell–mediated suppression

Tobias Bopp, Christian Becker, Matthias Klein, Stefan Klein-Heßling, Alois Palmetshofer, Edgar Serfling, Valeska Heib, Marc Becker, Jan Kubach, Steffen Schmitt, Sabine Stoll, Hansjörg Schild, Martin S. Staege, Michael Stassen, Helmut Jonuleit, and Edgar Schmitt
J. Exp. Med. 2007 204: 1303-1310. Published online May 14 2007, 10.1084/jem.20062129. [Abstract] [Full Text] [PDF] [Supplemental Material Index]  

Zoonotic orthopoxviruses encode a high-affinity antagonist of NKG2D

Jessica A. Campbell, David S. Trossman, Wayne M. Yokoyama, and Leonidas N. Carayannopoulos
J. Exp. Med. 2007 204: 1311-1317. Published online Jun 4 2007, 10.1084/jem.20062026. [Abstract] [Full Text] [PDF]  

A novel inhibitor of the alternative pathway of complement reverses inflammation and bone destruction in experimental arthritis

Kenneth J. Katschke, Jr., Karim Y. Helmy, Micah Steffek, Hongkang Xi, JianPing Yin, Wyne P. Lee, Peter Gribling, Kai H. Barck, Richard A.D. Carano, Robin E. Taylor, Linda Rangell, Lauri Diehl, Philip E. Hass, Christian Wiesmann, and Menno van Lookeren Campagne
J. Exp. Med. 2007 204: 1319-1325. Published online Jun 4 2007, 10.1084/jem.20070432. [Abstract] [Full Text] [PDF] [Supplemental Material Index]  

CCR4-dependent regulatory T cell function in inflammatory bowel disease

Qian Yuan, Shannon K. Bromley, Terry K. Means, Krister J. Jones, Fumitaka Hayashi, Atul K. Bhan, and Andrew D. Luster
J. Exp. Med. 2007 204: 1327-1334. Published online Jun 4 2007, 10.1084/jem.20062076. [Abstract] [Full Text] [PDF]  

 

ARTICLES:

Altering the distribution of Foxp3⁺ regulatory T cells results in tissue-specific inflammatory disease

Blythe D. Sather, Piper Treuting, Nikole Perdue, Mike Miazgowicz, Jason D. Fontenot, Alexander Y. Rudensky, and Daniel J. Campbell
J. Exp. Med. 2007 204: 1335-1347. Published online Jun 4 2007, 10.1084/jem.20070081. [Abstract] [Full Text] [PDF] [Supplemental Material Index]  

Type I interferons produced by hematopoietic cells protect mice against lethal infection by mammalian reovirus

Cecilia Johansson, J. Denise Wetzel, JianPing He, Carmen Mikacenic, Terence S. Dermody, and Brian L. Kelsall
J. Exp. Med. 2007 204: 1349-1358. Published online May 14 2007, 10.1084/jem.20061587. [Abstract] [Full Text] [PDF] [Supplemental Material Index]  

Selective blockade of the inhibitory Fc receptor (FcRIIB) in human dendritic cells and monocytes induces a type I interferon response program

Kavita M. Dhodapkar, Devi Banerjee, John Connolly, Anjli Kukreja, Elyana Matayeva, Maria Concetta Veri, Jeffrey V. Ravetch, Ralph M. Steinman, and Madhav V. Dhodapkar
J. Exp. Med. 2007 204: 1359-1369. Published online May 14 2007, 10.1084/jem.20062545. [Abstract] [Full Text] [PDF] [Supplemental Material Index]  

Defects in coding joint formation in vivo in developing ATM-deficient B and T lymphocytes

Ching-Yu Huang, Girdhar G. Sharma, Laura M. Walker, Craig H. Bassing, Tej K. Pandita, and Barry P. Sleckman
J. Exp. Med. 2007 204: 1371-1381. Published online May 14 2007, 10.1084/jem.20061460. [Abstract] [Full Text] [PDF] [Supplemental Material Index]  

Mice lacking NKCC1 are protected from development of bacteremia and hypothermic sepsis secondary to bacterial pneumonia

MyTrang Nguyen, Amy J. Pace, and Beverly H. Koller
J. Exp. Med. 2007 204: 1383-1393. Published online May 21 2007, 10.1084/jem.20061205. [Abstract] [Full Text] [PDF]  

Selective suppression of dendritic cell functions by Mycobacterium ulcerans toxin mycolactone

Emmanuelle Coutanceau, Jeremie Decalf, Angelo Martino, Aurélie Babon, Nathalie Winter, Stewart T. Cole, Matthew L. Albert, and Caroline Demangel
J. Exp. Med. 2007 204: 1395-1403. Published online May 21 2007, 10.1084/jem.20070234. [Abstract] [Full Text] [PDF] [Supplemental Material Index]  

Immunization with vaccinia virus induces polyfunctional and phenotypically distinctive CD8⁺ T cell responses

Melissa L. Precopio, Michael R. Betts, Janie Parrino, David A. Price, Emma Gostick, David R. Ambrozak, Tedi E. Asher, Daniel C. Douek, Alexandre Harari, Giuseppe Pantaleo, Robert Bailer, Barney S. Graham, Mario Roederer, and Richard A. Koup
J. Exp. Med. 2007 204: 1405-1416. Published online May 29 2007, 10.1084/jem.20062363. [Abstract] [Full Text] [PDF] [Supplemental Material Index]  

Increased susceptibility to colitis and colorectal tumors in mice lacking core 3–derived O-glycans

Guangyu An, Bo Wei, Baoyun Xia, J. Michael McDaniel, Tongzhong Ju, Richard D. Cummings, Jonathan Braun, and Lijun Xia
J. Exp. Med. 2007 204: 1417-1429. Published online May 21 2007, 10.1084/jem.20061929. [Abstract] [Full Text] [PDF] [Supplemental Material Index]  

Distinct vascular endothelial growth factor signals for lymphatic vessel enlargement and sprouting

Maria Wirzenius, Tuomas Tammela, Marko Uutela, Yulong He, Teresa Odorisio, Giovanna Zambruno, Janice A. Nagy, Harold F. Dvorak, Seppo Ylä-Herttuala, Masabumi Shibuya, and Kari Alitalo
J. Exp. Med. 2007 204: 1431-1440. Published online May 29 2007, 10.1084/jem.20062642. [Abstract] [Full Text] [PDF] [Supplemental Material Index]  

Tumoricidal activity of TLR7/8-activated inflammatory dendritic cells

Georg Stary, Christine Bangert, Martina Tauber, Robert Strohal, Tamara Kopp, and Georg Stingl
J. Exp. Med. 2007 204: 1441-1451. Published online May 29 2007, 10.1084/jem.20070021. [Abstract] [Full Text] [PDF] [Supplemental Material Index]  

DNA damage-induced cellular senescence is sufficient to suppress tumorigenesis: a mouse model

Thang Van Nguyen, Nahum Puebla-Osorio, Hui Pang, Melanie E. Dujka, and Chengming Zhu
J. Exp. Med. 2007 204: 1453-1461. Published online May 29 2007, 10.1084/jem.20062453. [Abstract] [Full Text] [PDF] [Supplemental Material Index]  

MyD88-dependent expansion of an immature GR-1⁺CD11b⁺ population induces T cell suppression and Th2 polarization in sepsis

Matthew J. Delano, Philip O. Scumpia, Jason S. Weinstein, Dominique Coco, Srinivas Nagaraj, Kindra M. Kelly-Scumpia, Kerri A. O'Malley, James L. Wynn, Svetlana Antonenko, Samer Z. Al-Quran, Ryan Swan, Chun-Shiang Chung, Mark A. Atkinson, Reuben Ramphal, Dmitry I. Gabrilovich, Wesley H. Reeves, Alfred Ayala, Joseph Phillips, Drake LaFace, Paul G. Heyworth, Michael Clare-Salzler, and Lyle L. Moldawer
J. Exp. Med. 2007 204: 1463-1474. Published online Jun 4 2007, 10.1084/jem.20062602. [Abstract] [Full Text] [PDF] [Supplemental Material Index]  

Deubiquitinating enzyme CYLD negatively regulates the ubiquitin-dependent kinase Tak1 and prevents abnormal T cell responses

William W. Reiley, Wei Jin, Andrew Joon Lee, Ato Wright, Xuefeng Wu, Eric F. Tewalt, Timothy O. Leonard, Christopher C. Norbury, Leo Fitzpatrick, Minying Zhang, and Shao-Cong Sun
J. Exp. Med. 2007 204: 1475-1485. Published online Jun 4 2007, 10.1084/jem.20062694. [Abstract] [Full Text] [PDF] [Supplemental Material Index]  

Dendritic cell quiescence during systemic inflammation driven by LPS stimulation of radioresistant cells in vivo

Martijn A. Nolte, Salomé LeibundGut-Landmann, Olivier Joffre, and Caetano Reis e Sousa
J. Exp. Med. 2007 204: 1487-1501. Published online Jun 4 2007, 10.1084/jem.20070325. [Abstract] [Full Text] [PDF] [Supplemental Material Index]  

 

FROM THE JCB:

Building blood vessels—stem cell models in vascular biology

Lars Jakobsson, Johan Kreuger, and Lena Claesson-Welsh [Full Text]  

GPI-anchored receptor clusters transiently recruit Lyn and G for temporary cluster immobilization and Lyn activation: single-molecule tracking study 1

Kenichi G.N. Suzuki, Takahiro K. Fujiwara, Fumiyuki Sanematsu, Ryota Iino, Michael Edidin, and Akihiro Kusumi [Full Text]  

To see an article, click its [Full Text] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.

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TABLE OF CONTENTS