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[Cover Caption] Browse Issues:		Apr 16 2007; 204 (4)        IN THIS ISSUE        FROM THE ARCHIVE        COMMENTARIES        BRIEF DEFINITIVE REPORTS        ARTICLES        CORRECTIONS        FROM THE JCB        FROM J. GEN. PHYSIOL.
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[Index by Author]

 

IN THIS ISSUE:

IN THIS ISSUE [PDF]

Arming antitumor T cells [Full Text]  

Anti-SOX2 T cells may prevent myeloma [Full Text]  

A parasite's power play [Full Text]  

Jinxed mice [Full Text]  

Mucosal HIV transmission [Full Text]  

 

FROM THE ARCHIVE:

FROM THE ARCHIVE [PDF]

Hormones and breast cancer: controlling the danger within [Abstract] [Full Text]  

 

COMMENTARIES:

The discovery value of "Big Science"

José Esparza and Tadataka Yamada
J. Exp. Med. 2007 204: 701-704. Published online Apr 9 2007, 10.1084/jem.20070073. [Abstract] [Full Text] [PDF]  

 

BRIEF DEFINITIVE REPORTS:

Intrarectal transmission, systemic infection, and CD4⁺ T cell depletion in humanized mice infected with HIV-1

Zhifeng Sun, Paul W. Denton, Jacob D. Estes, Florence A. Othieno, Bangdong L. Wei, Anja K. Wege, Michael W. Melkus, Angela Padgett-Thomas, Mary Zupancic, Ashley T. Haase, and J. Victor Garcia
J. Exp. Med. 2007 204: 705-714. Published online Mar 26 2007, 10.1084/jem.20062411. [Abstract] [Full Text] [PDF] [Supplemental Material Index]  

De novo DNA methyltransferase is essential for self-renewal, but not for differentiation, in hematopoietic stem cells

Yuko Tadokoro, Hideo Ema, Masaki Okano, En Li, and Hiromitsu Nakauchi
J. Exp. Med. 2007 204: 715-722. Published online Apr 9 2007, 10.1084/jem.20060750. [Abstract] [Full Text] [PDF] [Supplemental Material Index]  

 

ARTICLES:

Regulatory T cells interfere with the development of bronchus-associated lymphoid tissue

Jessica R. Kocks, Ana Clara Marques Davalos-Misslitz, Gabriele Hintzen, Lars Ohl, and Reinhold Förster
J. Exp. Med. 2007 204: 723-734. Published online Mar 19 2007, 10.1084/jem.20061424. [Abstract] [Full Text] [PDF]  

CCR7 is required for the in vivo function of CD4⁺ CD25⁺ regulatory T cells

Martin A. Schneider, Josef G. Meingassner, Martin Lipp, Henrietta D. Moore, and Antal Rot
J. Exp. Med. 2007 204: 735-745. Published online Mar 19 2007, 10.1084/jem.20061405. [Abstract] [Full Text] [PDF] [Supplemental Material Index]  

IgG1 B cell receptor signaling is inhibited by CD22 and promotes the development of B cells whose survival is less dependent on Ig/ß

Ari Waisman, Manfred Kraus, Jane Seagal, Snigdha Ghosh, Doron Melamed, Jian Song, Yoshiteru Sasaki, Sabine Classen, Claudia Lutz, Frank Brombacher, Lars Nitschke, and Klaus Rajewsky
J. Exp. Med. 2007 204: 747-758. Published online Apr 9 2007, 10.1084/jem.20062024. [Abstract] [Full Text] [PDF] [Supplemental Material Index]  

Enhancement and suppression of signaling by the conserved tail of IgG memory–type B cell antigen receptors

Keisuke Horikawa, Stephen W. Martin, Sarah L. Pogue, Karlee Silver, Kaiman Peng, Kiyoshi Takatsu, and Christopher C. Goodnow
J. Exp. Med. 2007 204: 759-769. Published online Apr 9 2007, 10.1084/jem.20061923. [Abstract] [Full Text] [PDF] [Supplemental Material Index]  

Lymph node topology dictates T cell migration behavior

Joost B. Beltman, Athanasius F.M. Marée, Jennifer N. Lynch, Mark J. Miller, and Rob J. de Boer
J. Exp. Med. 2007 204: 771-780. Published online Mar 26 2007, 10.1084/jem.20061278. [Abstract] [Full Text] [PDF] [Supplemental Material Index]  

Diacylglycerol kinase regulates microbial recognition and host resistance to Toxoplasma gondii

Cheng-Hu Liu, Fabiana S. Machado, Rishu Guo, Kim E. Nichols, A. Wesley Burks, Julio C. Aliberti, and Xiao-Ping Zhong
J. Exp. Med. 2007 204: 781-792. Published online Mar 19 2007, 10.1084/jem.20061856. [Abstract] [Full Text] [PDF]  

The humoral pattern recognition receptor PTX3 is stored in neutrophil granules and localizes in extracellular traps

Sébastien Jaillon, Giuseppe Peri, Yves Delneste, Isabelle Frémaux, Andrea Doni, Federica Moalli, Cecilia Garlanda, Luigina Romani, Hugues Gascan, Silvia Bellocchio, Silvia Bozza, Marco A. Cassatella, Pascale Jeannin, and Alberto Mantovani
J. Exp. Med. 2007 204: 793-804. Published online Mar 26 2007, 10.1084/jem.20061301. [Abstract] [Full Text] [PDF] [Supplemental Material Index]  

Splenic accumulation of IL-10 mRNA in T cells distinct from CD4⁺CD25⁺ (Foxp3) regulatory T cells in human visceral leishmaniasis

Susanne Nylén, Radheshyam Maurya, Liv Eidsmo, Krishna Das Manandhar, Shyam Sundar, and David Sacks
J. Exp. Med. 2007 204: 805-817. Published online Mar 26 2007, 10.1084/jem.20061141. [Abstract] [Full Text] [PDF]  

Repression of BCL-6 is required for the formation of human memory B cells in vitro

Tracy C. Kuo, Arthur L. Shaffer, Joseph Haddad, Jr., Yong Sung Choi, Louis M. Staudt, and Kathryn Calame
J. Exp. Med. 2007 204: 819-830. Published online Apr 2 2007, 10.1084/jem.20062104. [Abstract] [Full Text] [PDF] [Supplemental Material Index]  

Frequent and specific immunity to the embryonal stem cell–associated antigen SOX2 in patients with monoclonal gammopathy

Radek Spisek, Anjli Kukreja, Lin-Chi Chen, Phillip Matthews, Amitabha Mazumder, David Vesole, Sundar Jagannath, Henry A. Zebroski, Andrew J.G. Simpson, Gerd Ritter, Brian Durie, John Crowley, John D. Shaughnessy, Jr., Matthew J. Scanlan, Ali O. Gure, Bart Barlogie, and Madhav V. Dhodapkar
J. Exp. Med. 2007 204: 831-840. Published online Mar 26 2007, 10.1084/jem.20062387. [Abstract] [Full Text] [PDF] [Supplemental Material Index]  

The Niemann-Pick type C2 protein loads isoglobotrihexosylceramide onto CD1d molecules and contributes to the thymic selection of NKT cells

Nicolas Schrantz, Yuval Sagiv, Yang Liu, Paul B. Savage, Albert Bendelac, and Luc Teyton
J. Exp. Med. 2007 204: 841-852. Published online Mar 26 2007, 10.1084/jem.20061562. [Abstract] [Full Text] [PDF] [Supplemental Material Index]  

Jinx, an MCMV susceptibility phenotype caused by disruption of Unc13d: a mouse model of type 3 familial hemophagocytic lymphohistiocytosis

Karine Crozat, Kasper Hoebe, Sophie Ugolini, Nancy A. Hong, Edith Janssen, Sophie Rutschmann, Suzanne Mudd, Sosathya Sovath, Eric Vivier, and Bruce Beutler
J. Exp. Med. 2007 204: 853-863. Published online Apr 9 2007, 10.1084/jem.20062447. [Abstract] [Full Text] [PDF] [Supplemental Material Index]  

Importance of group X–secreted phospholipase A₂ in allergen-induced airway inflammation and remodeling in a mouse asthma model

William R. Henderson, Jr., Emil Y. Chi, James G. Bollinger, Ying-tzang Tien, Xin Ye, Luca Castelli, Yuri P. Rubtsov, Alan G. Singer, Gertrude K.S. Chiang, Timo Nevalainen, Alexander Y. Rudensky, and Michael H. Gelb
J. Exp. Med. 2007 204: 865-877. Published online Apr 2 2007, 10.1084/jem.20070029. [Abstract] [Full Text] [PDF] [Supplemental Material Index]  

Spontaneous tumor rejection by cbl-b–deficient CD8⁺ T cells

Stefanie Loeser, Karin Loser, Martijn S. Bijker, Manu Rangachari, Sjoerd H. van der Burg, Teiji Wada, Stefan Beissert, Cornelis J.M. Melief, and Josef M. Penninger
J. Exp. Med. 2007 204: 879-891. Published online Apr 2 2007, 10.1084/jem.20061699. [Abstract] [Full Text] [PDF] [Supplemental Material Index]  

NK cell activation in visceral leishmaniasis requires TLR9, myeloid DCs, and IL-12, but is independent of plasmacytoid DCs

Ulrike Schleicher, Jan Liese, Ilka Knippertz, Claudia Kurzmann, Andrea Hesse, Antje Heit, Jens A.A. Fischer, Siegfried Weiss, Ulrich Kalinke, Stefanie Kunz, and Christian Bogdan
J. Exp. Med. 2007 204: 893-906. Published online Mar 26 2007, 10.1084/jem.20061293. [Abstract] [Full Text] [PDF] [Supplemental Material Index]  

Cis binding between inhibitory receptors and MHC class I can regulate mast cell activation

Ai Masuda, Akira Nakamura, Tsutomu Maeda, Yuzuru Sakamoto, and Toshiyuki Takai
J. Exp. Med. 2007 204: 907-920. Published online Apr 9 2007, 10.1084/jem.20060631. [Abstract] [Full Text] [PDF]  

A distal effect of microsomal triglyceride transfer protein deficiency on the lysosomal recycling of CD1d

Yuval Sagiv, Li Bai, Datsen G. Wei, Reuven Agami, Paul B. Savage, Luc Teyton, and Albert Bendelac
J. Exp. Med. 2007 204: 921-928. Published online Apr 2 2007, 10.1084/jem.20061568. [Abstract] [Full Text] [PDF]  

Thromboxane A₂ is a key regulator of pathogenesis during Trypanosoma cruzi infection

Anthony W. Ashton, Shankar Mukherjee, FNU Nagajyothi, Huan Huang, Vicki L. Braunstein, Mahalia S. Desruisseaux, Stephen M. Factor, Lillie Lopez, Joan W. Berman, Murray Wittner, Philipp E. Scherer, Valerie Capra, Thomas M. Coffman, Charles N. Serhan, Katherine Gotlinger, Kenneth K. Wu, Louis M. Weiss, and Herbert B. Tanowitz
J. Exp. Med. 2007 204: 929-940. Published online Apr 9 2007, 10.1084/jem.20062432. [Abstract] [Full Text] [PDF]  

Viral antigen and extensive division maintain virus-specific CD8 T cells during chronic infection

Haina Shin, Shawn D. Blackburn, Joseph N. Blattman, and E. John Wherry
J. Exp. Med. 2007 204: 941-949. Published online Apr 9 2007, 10.1084/jem.20061937. [Abstract] [Full Text] [PDF]  

Antiviral CD4⁺ memory T cells are IL-15 dependent

Jared F. Purton, Joyce T. Tan, Mark P. Rubinstein, David M. Kim, Jonathan Sprent, and Charles D. Surh
J. Exp. Med. 2007 204: 951-961. Published online Apr 9 2007, 10.1084/jem.20061805. [Abstract] [Full Text] [PDF] [Supplemental Material Index]  

 

CORRECTIONS:

Enhanced mast cell activation in mice deficient in the A2b adenosine receptor

Xiaoyang Hua, Martina Kovarova, Kelly D. Chason, MyTrang Nguyen, Beverly H. Koller, and Stephen L. Tilley
J. Exp. Med. 2007 204: 963. Published online Apr 9 2007, 10.1084/jem.20061372032807c. [Full Text] [PDF]  

 

FROM THE JCB:

ASK1-dependent recruitment and activation of macrophages induce hair growth in skin wounds

Nao Osaka, Takumi Takahashi, Shiori Murakami, Atsushi Matsuzawa, Takuya Noguchi, Takeshi Fujiwara, Hiroyuki Aburatani, Keiji Moriyama, Kohsuke Takeda, and Hidenori Ichijo [Full Text]  

The actin-based motor protein myosin II regulates MHC class II trafficking and BCR-driven antigen presentation

Fulvia Vascotto, Danielle Lankar, Gabrielle Faure-André, Pablo Vargas, Jheimmy Diaz, Delphine Le Roux, Maria-Isabel Yuseff, Jean-Baptiste Sibarita, Marianne Boes, Graça Raposo, Evelyne Mougneau, Nicolas Glaichenhaus, Christian Bonnerot, Bénédicte Manoury, and Ana-Maria Lennon-Duménil [Full Text]  

Error bars in experimental biology

Geoff Cumming, Fiona Fidler, and David L. Vaux [Full Text]  

 

FROM J. GEN. PHYSIOL.:

Alteration of Epithelial Structure and Function Associated with PtdIns(4,5)P₂ Degradation by a Bacterial Phosphatase

David Mason, Gustavo V. Mallo, Mauricio R. Terebiznik, Bernard Payrastre, B. Brett Finlay, John H. Brumell, Lucia Rameh, and Sergio Grinstein [Full Text]  

To see an article, click its [Full Text] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.

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TABLE OF CONTENTS