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Cover picture: Defective ribosomal products (DRiPs) of the Epstein-Barr virus nuclear antigen EBNA1 are degraded by the proteasome for MHC class I presentation. Full-length EBNA1 is not degraded by the proteasome and might be the source of MCH class II ligands. EBNA1 released by dying EBV-transformed B cells is taken up by antigen-presenting cells and presented by MHC class I and II. See Commentary by Munz, pp. 1301-1304, and related articles by Lee et al., pp. 1409-1420, and Tellam et al., pp. 1421-1431.
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