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The Journal of Experimental Medicine 191 1 Cover picture: Ectopic formation of cartilage that undergoes endochondral ossification in extraarticular tissues of mice lacking the transcription factor NFATp. Comparison of radiograms of a wild-type (top right) and an NFATp^/- mouse (bottom left) shows multiple masses of calcified cartilage in the extraarticular tissue of the shoulder, hip, knee, and ankle joints of the NFATp^-/- mouse (arrows). Light microscopy (bottom right) shows cartilage, calcified cartilage, and bone formation in the connective tissue of the hip joint, compared with a control mouse (top left). See related article in this issue by Ranger et al., .
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