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Figure S1. H-CDR3 spectratypes of the VH3.30/33 and VH5.51 transcripts expressed by splenic B cell subsets of a 22-mo-old child (D4) and a 23-mo-old child (D7). Spectratyping was performed on μ transcripts from naive and IgD+CD27+ cells, and on γ transcripts from switched IgDCD27+ cells, as described. Peaks identified by an asterisk were further sequenced to evaluate intrapeak clonal diversity.