Table S2

APC

Cell type

Medium

IPP

Zoledronate

Daudi

Bone marrow B-cell lymphoma

2527*

14342

5647

THP-1

Bone marrow Monocytes

197

3153

16393

CEM 1.3

Bone marrow T-cell lymphoma

310

6586

1564

K562

Bone marrow Erythroleukemia

36

2762

1145

A-375

Skin Melanoma

188

9169

15842

A-431

Skin Epidermoid carcinoma

89

3269

3067

Colo 201

Colon epithelia Coloncarcinoma

260

3103

4374

HEP G2

Liver parenchyma Hepatocarcinoma

96

12040

12417

HuH6

Liver parenchyma Hepatoblastoma

80

4329

3451

A-243

Central nervous system Astrocytoma

23

5415

7141

U118

Central nervous system Glioblastoma

33

2114

5575

BS 125.3.2

Central nervous system Glioblastoma

46

13942

8440

MRK-nu-1

Mammary gland

35

3003

1965

 
Mammary carcinoma
     

HMC-1-8

Pleural effusion

17

2011

1845

 
Metastatic mammary carcinoma
     

YMB-1

Mammary gland Mammary carcinoma

1162

3695

1524

Fibroblasts Isolated from primary Lung connective tissue
175
5085
8767

Tumor cell linesof differenttissue originandprimary lung fibroblastswere pulsedwith 50 µg/ml Zoledronate for 3 h.IPP (10 �M) waspresentovernight.

*Numbersrepresentreleasedmeanpg/ml of TNF{alpha} by the G2B9 Tcell clone.