[HELP with High Resolution Image Viewing]

[View Larger Version of this Image]

Figure S1.Histology of spontaneousneoplasia inimmunodeficientmice.(A) Diffuse lymphoma (original magnification: 10X) infiltrating the liver of a B6 IFN-{gamma}-/- mouse. (B) Diffuse lymphoma (original magnification: 10X) infiltrating the liver of a B6 pfp-/- mouse showing significantdisruptionof normal organmorphology. (C) Normal liver (original magnification: 10X) showing normal hepatic architecture. D.Diffuse lymphoma (original magnification: 20X) infiltrating a spleenof a B6 pfp-/- mouse, which resemblesa large cell lymphoma. (E) BALB/c pfp-/- spleen(original magnification: 20X) with prominentinfiltrate of large cellswith pale, eosinophilic cytoplasm which onmorphological groundslookslike a histiocytic lymphoma. (F) Normal spleen(original magnification: 20X) with normal architecture. (G) Lung of BALB/c IFN-{gamma}-/- mouse (original magnification: 20X) showing a well-differentiatedlung papillary adenocarcinoma. (H) Lung of BALB/c pfp-/- mouse (original magnification: 20X) also showing a well-differentiatedlung papillary adenocarcinoma. (I) Normal lung (original magnification: 20X) with normal architecture.