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Issues

Volume 205, Issue 2
18 February 2008
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    ON THE COVER
    Vascular endothelial growth factor keeps specialized epithelial cells that line brain cavities alive. These cells prevent fluid produced by brain cells that protrude into the cavity from leaking into the brain. Related article by Maharaj et al.
    See page 491

  • PDF Icon PDF LinkTable of Contents
  • PDF Icon PDF LinkEditorial Board
ISSN 0022-1007
EISSN 1540-9538

Editorial

Irreproducible results: a response to Thomson Scientific
Mike Rossner,Heather Van Epps,Emma Hill
View Articletitled, Irreproducible results: a response to Thomson Scientific

In This Issue

Unmasking an inflammatory suppressor
Hema Bashyam
View Articletitled, Unmasking an inflammatory suppressor
Toll signals provoke plaque buildup
Hema Bashyam
View Articletitled, Toll signals provoke plaque buildup
Long-lasting Toll suppression
Hema Bashyam
View Articletitled, Long-lasting Toll suppression
Averting danger from within
Hema Bashyam
View Articletitled, Averting danger from within
VEGF blockade damages brain vessels
Hema Bashyam
View Articletitled, VEGF blockade damages brain vessels

People & Ideas

Anthony De Tomaso: Finding the origins of adaptive immunity
Hema Bashyam
View Articletitled, Anthony De Tomaso: Finding the origins of adaptive immunity

Commentary

Inciting inflammation: the RAGE about tumor promotion
Michael Dougan,Glenn Dranoff
View Articletitled, Inciting inflammation: the RAGE about tumor promotion
An antidote for Staphylococcus aureus pneumonia?
Frank R. DeLeo,Michael Otto
View Articletitled, An antidote for <em>Staphylococcus aureus</em> pneumonia?

Brief Definitive Report

RAGE signaling sustains inflammation and promotes tumor development
Christoffer Gebhardt,Astrid Riehl,Moritz Durchdewald,Julia Németh,Gerhard Fürstenberger,Karin Müller-Decker,Alexander Enk,Bernd Arnold,Angelika Bierhaus,Peter P. Nawroth,Jochen Hess,Peter Angel
View Articletitled, RAGE signaling sustains inflammation and promotes tumor development
Vaccine protection against Staphylococcus aureus pneumonia
Juliane Bubeck Wardenburg,Olaf Schneewind
View Articletitled, Vaccine protection against <em>Staphylococcus aureus</em> pneumonia
Periostin is essential for cardiac healingafter acute myocardial infarction
Masashi Shimazaki,Kazuto Nakamura,Isao Kii,Takeshi Kashima,Norio Amizuka,Minqi Li,Mitsuru Saito,Keiichi Fukuda,Takashi Nishiyama,Satoshi Kitajima,Yumiko Saga,Masashi Fukayama,Masataka Sata,Akira Kudo
View Articletitled, Periostin is essential for cardiac healingafter acute myocardial infarction
Forward genetic analysis of Toll-like receptor responses in wild-derived mice reveals a novel antiinflammatory role for IRAK1BP1
James R. Conner,Irina I. Smirnova,Alexander Poltorak
View Articletitled, Forward genetic analysis of Toll-like receptor responses in wild-derived mice reveals a novel antiinflammatory role for IRAK1BP1
PI3K is critical for the nuclear translocation of IRF-7 and type I IFN production by human plasmacytoid predendritic cells in response to TLR activation
Cristiana Guiducci,Cristina Ghirelli,Marie-Annick Marloie-Provost,Tracy Matray,Robert L. Coffman,Yong-Jun Liu,Franck J. Barrat,Vassili Soumelis
View Articletitled, PI3K is critical for the nuclear translocation of IRF-7 and type I IFN production by human plasmacytoid predendritic cells in response to TLR activation
Sustained desensitization to bacterial Toll-like receptor ligands after resolutionof respiratory influenza infection
Arnaud Didierlaurent,John Goulding,Seema Patel,Robert Snelgrove,Lionel Low,Magali Bebien,Toby Lawrence,Leonie S. van Rijt,Bart N. Lambrecht,Jean-Claude Sirard,Tracy Hussell
View Articletitled, Sustained desensitization to bacterial Toll-like receptor ligands after resolutionof respiratory influenza infection
Mesenchymal cell targeting by TNF as a common pathogenic principle in chronic inflammatory joint and intestinal diseases
Maria Armaka,Maria Apostolaki,Peggy Jacques,Dimitris L. Kontoyiannis,Dirk Elewaut,George Kollias
View Articletitled, Mesenchymal cell targeting by TNF as a common pathogenic principle in chronic inflammatory joint and intestinal diseases
IL-33 reduces the development of atherosclerosis
Ashley M. Miller,Damo Xu,Darren L. Asquith,Laura Denby,Yubin Li,Naveed Sattar,Andrew H. Baker,Iain B. McInnes,Foo Y. Liew
View Articletitled, IL-33 reduces the development of atherosclerosis

Article

iPLA2β: front and center in human monocyte chemotaxis to MCP-1
Ravi S. Mishra,Kevin A. Carnevale,Martha K. Cathcart
View Articletitled, iPLA<sub>2</sub>β: front and center in human monocyte chemotaxis to MCP-1
Pulmonary arterial remodeling induced by a Th2 immune response
Eleen Daley,Claire Emson,Christophe Guignabert,Rene de Waal Malefyt,Jennifer Louten,Viswanath P. Kurup,Cory Hogaboam,Laimute Taraseviciene-Stewart,Norbert F. Voelkel,Marlene Rabinovitch,Ekkehard Grunig,Gabriele Grunig
View Articletitled, Pulmonary arterial remodeling induced by a Th2 immune response
Increased endothelial expression of Toll-like receptor 2 at sites of disturbed blood flow exacerbates early atherogenic events
Adam E. Mullick,Katrin Soldau,William B. Kiosses,Thomas A. Bell, III,Peter S. Tobias,Linda K. Curtiss
View Articletitled, Increased endothelial expression of Toll-like receptor 2 at sites of disturbed blood flow exacerbates early atherogenic events
Ozone exposure in a mouse model induces airway hyperreactivity that requires the presence of natural killer T cells and IL-17
Muriel Pichavant,Sho Goya,Everett H. Meyer,Richard A. Johnston,Hye Y. Kim,Ponpan Matangkasombut,Ming Zhu,Yoichiro Iwakura,Paul B. Savage,Rosemarie H. DeKruyff,Stephanie A. Shore,Dale T. Umetsu
View Articletitled, Ozone exposure in a mouse model induces airway hyperreactivity that requires the presence of natural killer T cells and IL-17
Inhibition of histamine-mediated signaling confers significant protection against severe malaria in mouse models of disease
Walid Beghdadi,Adeline Porcherie,Bradley S. Schneider,David Dubayle,Roger Peronet,Michel Huerre,Takeshi Watanabe,Hiroshi Ohtsu,Jacques Louis,Salaheddine Mécheri
View Articletitled, Inhibition of histamine-mediated signaling confers significant protection against severe malaria in mouse models of disease
Oct2 enhances antibody-secreting cell differentiation through regulation of IL-5 receptor α chain expression on activated B cells
Dianne Emslie,Kathy D'Costa,Jhagvaral Hasbold,Donald Metcalf,Kiyoshi Takatsu,Philip O. Hodgkin,Lynn M. Corcoran
View Articletitled, Oct2 enhances antibody-secreting cell differentiation through regulation of IL-5 receptor α chain expression on activated B cells
Altered development of the brain after focal herpesvirus infection of the central nervous system
Thad Koontz,Marina Bralic,Jelena Tomac,Ester Pernjak-Pugel,Glen Bantug,Stipan Jonjic,William J. Britt
View Articletitled, Altered development of the brain after focal herpesvirus infection of the central nervous system
Microbe sampling by mucosal dendritic cells is a discrete, MyD88-independent stepin ΔinvG S. Typhimurium colitis
Siegfried Hapfelmeier,Andreas J. Müller,Bärbel Stecher,Patrick Kaiser,Manja Barthel,Kathrin Endt,Matthias Eberhard,Riccardo Robbiani,Christoph A. Jacobi,Mathias Heikenwalder,Carsten Kirschning,Steffen Jung,Thomas Stallmach,Marcus Kremer,Wolf-Dietrich Hardt
View Articletitled, Microbe sampling by mucosal dendritic cells is a discrete, MyD88-independent stepin Δ<em>invG S</em>. Typhimurium colitis
Homeostatic MyD88-dependent signals cause lethal inflamMation in the absence of A20
Emre E. Turer,Rita M. Tavares,Erwan Mortier,Osamu Hitotsumatsu,Rommel Advincula,Bettina Lee,Nataliya Shifrin,Barbara A. Malynn,Averil Ma
View Articletitled, Homeostatic MyD88-dependent signals cause lethal inflamMation in the absence of A20
Targeted inactivation of the COP9 signalosome impairs multiple stagesof T cell development
Martina Panattoni,Francesca Sanvito,Veronica Basso,Claudio Doglioni,Giulia Casorati,Eugenio Montini,Jeffrey R. Bender,Anna Mondino,Ruggero Pardi
View Articletitled, Targeted inactivation of the COP9 signalosome impairs multiple stagesof T cell development
Essential but differential role for CXCR4 and CXCR7 in the therapeutic homingof human renal progenitor cells
Benedetta Mazzinghi,Elisa Ronconi,Elena Lazzeri,Costanza Sagrinati,Lara Ballerini,Maria Lucia Angelotti,Eliana Parente,Rosa Mancina,Giuseppe Stefano Netti,Francesca Becherucci,Mauro Gacci,Marco Carini,Loreto Gesualdo,Mario Rotondi,Enrico Maggi,Laura Lasagni,Mario Serio,Sergio Romagnani,Paola Romagnani
View Articletitled, Essential but differential role for CXCR4 and CXCR7 in the therapeutic homingof human renal progenitor cells
VEGF and TGF-β are required for the maintenance of the choroid plexus and ependyma
Arindel S.R. Maharaj,Tony E. Walshe,Magali Saint-Geniez,Shivalingappa Venkatesha,Angel E. Maldonado,Nathan C. Himes,Kabir S. Matharu,S. Ananth Karumanchi,Patricia A. D'Amore
View Articletitled, VEGF and TGF-β are required for the maintenance of the choroid plexus and ependyma

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