Proliferation of latently infected CD4+ T cells carrying replication-competent HIV-1: Potential role in latent reservoir dynamics

Nina N. Hosmane; Kyungyoon J. Kwon; Katherine M. Bruner; Adam A. Capoferri; Subul Beg; Daniel I.S. Rosenbloom; Brandon F. Keele; Ya-Chi Ho; Janet D. Siliciano; Robert F. Siliciano

doi:10.1084/jem.20170193

Proliferation of latently infected CD4⁺ T cells carrying replication-competent HIV-1: Potential role in latent reservoir dynamics

Nina N. Hosmane, Kyungyoon J. Kwon, Katherine M. Bruner, Adam A. Capoferri, View ORCID ProfileSubul Beg, Daniel I.S. Rosenbloom, Brandon F. Keele, Ya-Chi Ho, View ORCID ProfileJanet D. Siliciano, View ORCID ProfileRobert F. Siliciano

Nina N. Hosmane

Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21205

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Kyungyoon J. Kwon

Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21205

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Katherine M. Bruner

Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21205

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Adam A. Capoferri

Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21205

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Subul Beg

Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21205

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ORCID record for Subul Beg

Daniel I.S. Rosenbloom

Department of Biomedical Informatics, Columbia University Medical Center, New York, NY 10032

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Brandon F. Keele

AIDS and Cancer Virus Program, Leidos Biomedical Research Inc., Frederick National Laboratory for Cancer Research, Frederick, MD 21702

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Ya-Chi Ho

Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21205

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Janet D. Siliciano

Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21205

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Robert F. Siliciano

Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21205Howard Hughes Medical Institute, Baltimore, MD 21205

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ORCID record for Robert F. Siliciano

DOI: 10.1084/jem.20170193 | Published March 24, 2017

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Proliferation of latently infected CD4⁺ T cells carrying replication-competent HIV-1: Potential role in latent reservoir dynamics

Nina N. Hosmane, Kyungyoon J. Kwon, Katherine M. Bruner, Adam A. Capoferri, Subul Beg, Daniel I.S. Rosenbloom, Brandon F. Keele, Ya-Chi Ho, Janet D. Siliciano, Robert F. Siliciano

Journal of Experimental Medicine Apr 2017, 214 (4) 959-972; DOI: 10.1084/jem.20170193