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jem Home » 1908 Archive » 8 July » 10 (4): 559
Article

THE HUMAN SPLEEN AS AN HÆMATOPLASTIC ORGAN, AS EXEMPLIFIED IN A CASE OF SPLENOMEGALY WITH SCLEROSIS OF THE BONE-MARROW

J. L. Donhauser
J. L. Donhauser
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DOI: 10.1084/jem.10.4.559 | Published July 8, 1908
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Abstract

1. The nodules found in the spleen are islands of active hæmatoplastic tissue.

2. The bone-marrow, at least in the case which has been described, has been the primary focus of disease; some toxin has probably produced a chronic inflammatory change.

3. The bone-marrow, owing to its enormous sclerosis, has lost its hæmopoëtic powers totally or to a marked degree and the spleen has reverted to its fœtal power to form blood.

Footnotes

    • Submitted: 3 April 1908
© 1908 Rockefeller University Press
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THE HUMAN SPLEEN AS AN HÆMATOPLASTIC ORGAN, AS EXEMPLIFIED IN A CASE OF SPLENOMEGALY WITH SCLEROSIS OF THE BONE-MARROW
J. L. Donhauser
Journal of Experimental Medicine Jul 1908, 10 (4) 559-574; DOI: 10.1084/jem.10.4.559

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The Journal of Experimental Medicine: 215 (4)

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April 2, 2018
Volume 215, No. 4

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