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Stem Cells & Regeneration

  • Stem Cells & Regeneration
  • SHP-1 regulates hematopoietic stem cell quiescence by coordinating TGF-β signaling
    SHP-1 regulates hematopoietic stem cell quiescence by coordinating TGF-β signaling
    Linjia Jiang, Xue Han, Jin Wang, Chen Wang, Xiaoqiang Sun, Jiayi Xie, Guojin Wu, Hiep Phan, Zhenguo Liu, ChengCheng Zhang, Meng Zhao, Xunlei Kang
    Journal of Experimental Medicine Apr 2018, jem.20171477; DOI: 10.1084/jem.20171477
  • Death, eaters, and dark marks
    Death, eaters, and dark marks
    Matthew Collin
    Journal of Experimental Medicine Apr 2018, 215 (4) 1005-1006; DOI: 10.1084/jem.20180311
  • Obesity alters the long-term fitness of the hematopoietic stem cell compartment through modulation of <em>Gfi1</em> expression
    Obesity alters the long-term fitness of the hematopoietic stem cell compartment through modulation of Gfi1 expression
    Jung-Mi Lee, Vinothini Govindarajah, Bryan Goddard, Ashwini Hinge, David E. Muench, Marie-Dominique Filippi, Bruce Aronow, Jose A. Cancelas, Nathan Salomonis, H. Leighton Grimes, Damien Reynaud
    Journal of Experimental Medicine Feb 2018, 215 (2) 627-644; DOI: 10.1084/jem.20170690
  • A molecular roadmap of the AGM region reveals BMPER as a novel regulator of HSC maturation
    A molecular roadmap of the AGM region reveals BMPER as a novel regulator of HSC maturation
    Alison C. McGarvey, Stanislav Rybtsov, Céline Souilhol, Sara Tamagno, Ritva Rice, David Hills, Duncan Godwin, David Rice, Simon R. Tomlinson, Alexander Medvinsky
    Journal of Experimental Medicine Dec 2017, 214 (12) 3731-3751; DOI: 10.1084/jem.20162012
  • Human stem cell–derived astrocytes replicate human prions in a <em>PRNP</em> genotype–dependent manner
    Human stem cell–derived astrocytes replicate human prions in a PRNP genotype–dependent manner
    Zuzana Krejciova, James Alibhai, Chen Zhao, Robert Krencik, Nina M. Rzechorzek, Erik M. Ullian, Jean Manson, James W. Ironside, Mark W. Head, Siddharthan Chandran
    Journal of Experimental Medicine Dec 2017, 214 (12) 3481-3495; DOI: 10.1084/jem.20161547
  • Dissecting hematopoietic and renal cell heterogeneity in adult zebrafish at single-cell resolution using RNA sequencing
    Dissecting hematopoietic and renal cell heterogeneity in adult zebrafish at single-cell resolution using RNA sequencing
    Qin Tang, Sowmya Iyer, Riadh Lobbardi, John C. Moore, Huidong Chen, Caleb Lareau, Christine Hebert, McKenzie L. Shaw, Cyril Neftel, Mario L. Suva, Craig J. Ceol, Andre Bernards, Martin Aryee, Luca Pinello, Iain A. Drummond, David M. Langenau
    Journal of Experimental Medicine Oct 2017, 214 (10) 2875-2887; DOI: 10.1084/jem.20170976
  • <em>miR-99</em> regulates normal and malignant hematopoietic stem cell self-renewal
    miR-99 regulates normal and malignant hematopoietic stem cell self-renewal
    Mona Khalaj, Carolien M. Woolthuis, Wenhuo Hu, Benjamin H. Durham, S. Haihua Chu, Sarah Qamar, Scott A. Armstrong, Christopher Y. Park
    Journal of Experimental Medicine Aug 2017, 214 (8) 2453-2470; DOI: 10.1084/jem.20161595
  • Rb family proteins enforce the homeostasis of quiescent hematopoietic stem cells by repressing Socs3 expression
    Rb family proteins enforce the homeostasis of quiescent hematopoietic stem cells by repressing Socs3 expression
    Eunsun Kim, Ying Cheng, Elisabeth Bolton-Gillespie, Xiongwei Cai, Connie Ma, Amy Tarangelo, Linh Le, Madhumita Jambhekar, Pichai Raman, Katharina E. Hayer, Gerald Wertheim, Nancy A. Speck, Wei Tong, Patrick Viatour
    Journal of Experimental Medicine Jul 2017, 214 (7) 1901-1912; DOI: 10.1084/jem.20160719
  • Niche-mediated depletion of the normal hematopoietic stem cell reservoir by Flt3-ITD–induced myeloproliferation
    Niche-mediated depletion of the normal hematopoietic stem cell reservoir by Flt3-ITD–induced myeloproliferation
    Adam J. Mead, Wen Hao Neo, Nikolaos Barkas, Sahoko Matsuoka, Alice Giustacchini, Raffaella Facchini, Supat Thongjuea, Lauren Jamieson, Christopher A.G. Booth, Nicholas Fordham, Cristina Di Genua, Deborah Atkinson, Onima Chowdhury, Emmanouela Repapi, Nicki Gray, Shabnam Kharazi, Sally-Ann Clark, Tiphaine Bouriez, Petter Woll, Toshio Suda, Claus Nerlov, Sten Eirik W. Jacobsen
    Journal of Experimental Medicine Jul 2017, 214 (7) 2005-2021; DOI: 10.1084/jem.20161418
  • A transit-amplifying population underpins the efficient regenerative capacity of the testis
    A transit-amplifying population underpins the efficient regenerative capacity of the testis
    Claudia Carrieri, Stefano Comazzetto, Amit Grover, Marcos Morgan, Andreas Buness, Claus Nerlov, Dónal O’Carroll
    Journal of Experimental Medicine Jun 2017, 214 (6) 1631-1641; DOI: 10.1084/jem.20161371

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