Stem Cells & Regeneration

Stem Cells & Regeneration

Ca²⁺–mitochondria axis drives cell division in hematopoietic stem cells
Terumasa Umemoto, Michihiro Hashimoto, Takayoshi Matsumura, Ayako Nakamura-Ishizu, Toshio Suda

Journal of Experimental Medicine Aug 2018, 215 (8) 2097-2113; DOI: 10.1084/jem.20180421
Ca²⁺tapulting HSCs into action
Amelie V. Guitart, Andrew J. Finch, Kamil R. Kranc

Journal of Experimental Medicine Aug 2018, 215 (8) 1971-1973; DOI: 10.1084/jem.20181097
miR-196b target screen reveals mechanisms maintaining leukemia stemness with therapeutic potential
Sara E. Meyer, David E. Muench, Andrew M. Rogers, Tess J. Newkold, Emily Orr, Eric O’Brien, John P. Perentesis, John G. Doench, Ashish Lal, Patrick J. Morris, Craig J. Thomas, Judy Lieberman, Edwina McGlinn, Bruce J. Aronow, Nathan Salomonis, H. Leighton Grimes

Journal of Experimental Medicine Aug 2018, 215 (8) 2115-2136; DOI: 10.1084/jem.20171312
Itraconazole targets cell cycle heterogeneity in colorectal cancer
Simon J.A. Buczacki, Semiramis Popova, Emma Biggs, Chrysa Koukorava, Jon Buzzelli, Louis Vermeulen, Lee Hazelwood, Hayley Francies, Mathew J. Garnett, Douglas J. Winton

Journal of Experimental Medicine Jul 2018, 215 (7) 1891-1912; DOI: 10.1084/jem.20171385
SHP-1 regulates hematopoietic stem cell quiescence by coordinating TGF-β signaling
Linjia Jiang, Xue Han, Jin Wang, Chen Wang, Xiaoqiang Sun, Jiayi Xie, Guojin Wu, Hiep Phan, Zhenguo Liu, Edward T.H. Yeh, ChengCheng Zhang, Meng Zhao, Xunlei Kang

Journal of Experimental Medicine May 2018, 215 (5) 1337-1347; DOI: 10.1084/jem.20171477
Death, eaters, and dark marks
Matthew Collin

Journal of Experimental Medicine Apr 2018, 215 (4) 1005-1006; DOI: 10.1084/jem.20180311
Obesity alters the long-term fitness of the hematopoietic stem cell compartment through modulation of Gfi1 expression
Jung-Mi Lee, Vinothini Govindarajah, Bryan Goddard, Ashwini Hinge, David E. Muench, Marie-Dominique Filippi, Bruce Aronow, Jose A. Cancelas, Nathan Salomonis, H. Leighton Grimes, Damien Reynaud

Journal of Experimental Medicine Feb 2018, 215 (2) 627-644; DOI: 10.1084/jem.20170690
A molecular roadmap of the AGM region reveals BMPER as a novel regulator of HSC maturation
Alison C. McGarvey, Stanislav Rybtsov, Céline Souilhol, Sara Tamagno, Ritva Rice, David Hills, Duncan Godwin, David Rice, Simon R. Tomlinson, Alexander Medvinsky

Journal of Experimental Medicine Dec 2017, 214 (12) 3731-3751; DOI: 10.1084/jem.20162012
Human stem cell–derived astrocytes replicate human prions in a PRNP genotype–dependent manner
Zuzana Krejciova, James Alibhai, Chen Zhao, Robert Krencik, Nina M. Rzechorzek, Erik M. Ullian, Jean Manson, James W. Ironside, Mark W. Head, Siddharthan Chandran

Journal of Experimental Medicine Dec 2017, 214 (12) 3481-3495; DOI: 10.1084/jem.20161547
Dissecting hematopoietic and renal cell heterogeneity in adult zebrafish at single-cell resolution using RNA sequencing
Qin Tang, Sowmya Iyer, Riadh Lobbardi, John C. Moore, Huidong Chen, Caleb Lareau, Christine Hebert, McKenzie L. Shaw, Cyril Neftel, Mario L. Suva, Craig J. Ceol, Andre Bernards, Martin Aryee, Luca Pinello, Iain A. Drummond, David M. Langenau

Journal of Experimental Medicine Oct 2017, 214 (10) 2875-2887; DOI: 10.1084/jem.20170976

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