Mucosal Immunology

Mucosal Immunology

Subset- and tissue-defined STAT5 thresholds control homeostasis and function of innate lymphoid cells
Alejandro V. Villarino, Giuseppe Sciumè, Fred P. Davis, Shigeru Iwata, Beatrice Zitti, Gertraud W. Robinson, Lothar Hennighausen, Yuka Kanno, John J. O’Shea

Journal of Experimental Medicine Sep 2017, jem.20150907; DOI: 10.1084/jem.20150907
Reduced generation of lung tissue–resident memory T cells during infancy
Kyra D. Zens, Jun Kui Chen, Rebecca S. Guyer, Felix L. Wu, Filip Cvetkovski, Michelle Miron, Donna L. Farber

Journal of Experimental Medicine Aug 2017, jem.20170521; DOI: 10.1084/jem.20170521
IL-22 induces Reg3γ and inhibits allergic inflammation in house dust mite–induced asthma models
Takashi Ito, Koichi Hirose, Aiko Saku, Kenta Kono, Hiroaki Takatori, Tomohiro Tamachi, Yoshiyuki Goto, Jean-Christophe Renauld, Hiroshi Kiyono, Hiroshi Nakajima

Journal of Experimental Medicine Aug 2017, jem.20162108; DOI: 10.1084/jem.20162108
PPARγ in dendritic cells and T cells drives pathogenic type-2 effector responses in lung inflammation
Samuel Philip Nobs, Sara Natali, Lea Pohlmeier, Katarzyna Okreglicka, Christoph Schneider, Michael Kurrer, Federica Sallusto, Manfred Kopf

Journal of Experimental Medicine Aug 2017, jem.20162069; DOI: 10.1084/jem.20162069
Thymic progenitors of TCRαβ⁺ CD8αα intestinal intraepithelial lymphocytes require RasGRP1 for development
Dominic P. Golec, Romy E. Hoeppli, Laura M. Henao Caviedes, Jillian McCann, Megan K. Levings, Troy A. Baldwin

Journal of Experimental Medicine Aug 2017, 214 (8) 2421-2435; DOI: 10.1084/jem.20170844
Intestinal epithelial cell endoplasmic reticulum stress promotes MULT1 up-regulation and NKG2D-mediated inflammation
Shuhei Hosomi, Joep Grootjans, Markus Tschurtschenthaler, Niklas Krupka, Juan D. Matute, Magdalena B. Flak, Eduardo Martinez-Naves, Manuel Gomez del Moral, Jonathan N. Glickman, Mizuki Ohira, Lewis L. Lanier, Arthur Kaser, Richard Blumberg

Journal of Experimental Medicine Jul 2017, jem.20162041; DOI: 10.1084/jem.20162041
Human RELA haploinsufficiency results in autosomal-dominant chronic mucocutaneous ulceration
Yousef R. Badran, Fatma Dedeoglu, Juan Manuel Leyva Castillo, Wayne Bainter, Toshiro K. Ohsumi, Athos Bousvaros, Jeffrey D. Goldsmith, Raif S. Geha, Janet Chou

Journal of Experimental Medicine Jul 2017, 214 (7) 1937-1947; DOI: 10.1084/jem.20160724
Interleukin 4 promotes the development of ex-Foxp3 Th2 cells during immunity to intestinal helminths
Victoria S. Pelly, Stephanie M. Coomes, Yashaswini Kannan, Manolis Gialitakis, Lewis J. Entwistle, Jimena Perez-Lloret, Stephanie Czieso, Isobel S. Okoye, Dominik Rückerl, Judith E. Allen, Frank Brombacher, Mark S. Wilson

Journal of Experimental Medicine Jun 2017, 214 (6) 1809-1826; DOI: 10.1084/jem.20161104
IL-22BP dictates characteristics of Peyer’s patch follicle-associated epithelium for antigen uptake
Toshi Jinnohara, Takashi Kanaya, Koji Hase, Sayuri Sakakibara, Tamotsu Kato, Naoko Tachibana, Takaharu Sasaki, Yusuke Hashimoto, Toshiro Sato, Hiroshi Watarai, Jun Kunisawa, Naoko Shibata, Ifor R. Williams, Hiroshi Kiyono, Hiroshi Ohno

Journal of Experimental Medicine Jun 2017, 214 (6) 1607-1618; DOI: 10.1084/jem.20160770
Myeloid-derived miR-223 regulates intestinal inflammation via repression of the NLRP3 inflammasome
Viola Neudecker, Moritz Haneklaus, Owen Jensen, Ludmila Khailova, Joanne C. Masterson, Hazel Tye, Kathryn Biette, Paul Jedlicka, Kelley S. Brodsky, Mark E. Gerich, Matthias Mack, Avril A.B. Robertson, Matthew A. Cooper, Glenn T. Furuta, Charles A. Dinarello, Luke A. O’Neill, Holger K. Eltzschig, Seth L. Masters, Eóin N. McNamee

Journal of Experimental Medicine Jun 2017, 214 (6) 1737-1752; DOI: 10.1084/jem.20160462

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