Cardiovascular Biology

Cardiovascular Biology

Human venous valve disease caused by mutations in FOXC2 and GJC2
Oliver Lyons, Prakash Saha, Christopher Seet, Adam Kuchta, Andrew Arnold, Steven Grover, Victoria Rashbrook, Amélie Sabine, Gema Vizcay-Barrena, Ash Patel, Francesca Ludwinski, Soundrie Padayachee, Tsutomu Kume, Brenda R. Kwak, Glen Brice, Sahar Mansour, Pia Ostergaard, Peter Mortimer, Steve Jeffery, Nigel Brown, Taija Makinen, Tatiana V. Petrova, Bijan Modarai, Alberto Smith

Journal of Experimental Medicine Jul 2017, jem.20160875; DOI: 10.1084/jem.20160875
Platelets as autonomous drones for hemostatic and immune surveillance
Jackson LiangYao Li, Alexander Zarbock, Andrés Hidalgo

Journal of Experimental Medicine Jul 2017, jem.20170879; DOI: 10.1084/jem.20170879
Therapeutic antibody targeting of Notch3 signaling prevents mural cell loss in CADASIL
Arturo I. Machuca-Parra, Alexander A. Bigger-Allen, Angie V. Sanchez, Anissa Boutabla, Jonathan Cardona-Vélez, Dhanesh Amarnani, Magali Saint-Geniez, Christian W. Siebel, Leo A. Kim, Patricia A. D’Amore, Joseph F. Arboleda-Velasquez

Journal of Experimental Medicine Jul 2017, jem.20161715; DOI: 10.1084/jem.20161715
Annexin A2 supports pulmonary microvascular integrity by linking vascular endothelial cadherin and protein tyrosine phosphatases
Min Luo, Elle C. Flood, Dena Almeida, LunBiao Yan, David A. Berlin, Paul M. Heerdt, Katherine A. Hajjar

Journal of Experimental Medicine Jul 2017, jem.20160652; DOI: 10.1084/jem.20160652
Enzymatic lipid oxidation by eosinophils propagates coagulation, hemostasis, and thrombotic disease
Stefan Uderhardt, Jochen A. Ackermann, Tobias Fillep, Victoria J. Hammond, Johann Willeit, Peter Santer, Manuel Mayr, Markus Biburger, Meike Miller, Katie R. Zellner, Konstantin Stark, Alexander Zarbock, Jan Rossaint, Irene Schubert, Dirk Mielenz, Barbara Dietel, Dorette Raaz-Schrauder, Cihan Ay, Thomas Gremmel, Johannes Thaler, Christian Heim, Martin Herrmann, Peter W. Collins, Gernot Schabbauer, Nigel Mackman, David Voehringer, Jerry L. Nadler, James J. Lee, Steffen Massberg, Manfred Rauh, Stefan Kiechl, Georg Schett, Valerie B. O’Donnell, Gerhard Krönke

Journal of Experimental Medicine Jul 2017, 214 (7) 2121-2138; DOI: 10.1084/jem.20161070
Corticotropin releasing hormone receptor 2 exacerbates chronic cardiac dysfunction
Takuma Tsuda, Mikito Takefuji, Nina Wettschureck, Kazuhiko Kotani, Ryota Morimoto, Takahiro Okumura, Harmandeep Kaur, Shunsuke Eguchi, Teruhiro Sakaguchi, Sohta Ishihama, Ryosuke Kikuchi, Kazumasa Unno, Kunihiro Matsushita, Shizukiyo Ishikawa, Stefan Offermanns, Toyoaki Murohara

Journal of Experimental Medicine Jul 2017, 214 (7) 1877-1888; DOI: 10.1084/jem.20161924
Inflammatory signals from photoreceptor modulate pathological retinal angiogenesis via c-Fos
Ye Sun, Zhiqiang Lin, Chi-Hsiu Liu, Yan Gong, Raffael Liegl, Thomas W. Fredrick, Steven S. Meng, Samuel B. Burnim, Zhongxiao Wang, James D. Akula, William T. Pu, Jing Chen, Lois E.H. Smith

Journal of Experimental Medicine Jun 2017, 214 (6) 1753-1767; DOI: 10.1084/jem.20161645
Secretogranin III as a disease-associated ligand for antiangiogenic therapy of diabetic retinopathy
Michelle E. LeBlanc, Weiwen Wang, Xiuping Chen, Nora B. Caberoy, Feiye Guo, Chen Shen, Yanli Ji, Hong Tian, Hui Wang, Rui Chen, Wei Li

Journal of Experimental Medicine Apr 2017, 214 (4) 1029-1047; DOI: 10.1084/jem.20161802
Eosinophil-derived IL-4 drives progression of myocarditis to inflammatory dilated cardiomyopathy
Nicola L. Diny, G. Christian Baldeviano, Monica V. Talor, Jobert G. Barin, SuFey Ong, Djahida Bedja, Allison G. Hays, Nisha A. Gilotra, Isabelle Coppens, Noel R. Rose, Daniela Čiháková

Journal of Experimental Medicine Apr 2017, 214 (4) 943-957; DOI: 10.1084/jem.20161702
VEGF165-induced vascular permeability requires NRP1 for ABL-mediated SRC family kinase activation
Alessandro Fantin, Anastasia Lampropoulou, Valentina Senatore, James T. Brash, Claudia Prahst, Clemens A. Lange, Sidath E. Liyanage, Claudio Raimondi, James W. Bainbridge, Hellmut G. Augustin, Christiana Ruhrberg

Journal of Experimental Medicine Apr 2017, 214 (4) 1049-1064; DOI: 10.1084/jem.20160311

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