Cardiovascular Biology

  • Midkine drives cardiac inflammation by promoting neutrophil trafficking and NETosis in myocarditis
    Midkine drives cardiac inflammation by promoting neutrophil trafficking and NETosis in myocarditis
    Ludwig T. Weckbach, Ulrich Grabmaier, Andreas Uhl, Sebastian Gess, Felicitas Boehm, Annette Zehrer, Robert Pick, Melanie Salvermoser, Thomas Czermak, Joachim Pircher, Noah Sorrelle, Mary Migliorini, Dudley K. Strickland, Karin Klingel, Volker Brinkmann, Ulrike Abu Abed, Urs Eriksson, Steffen Massberg, Stefan Brunner, Barbara Walzog
    Journal of Experimental Medicine Feb 2019, 216 (2) 350-368; DOI: 10.1084/jem.20181102
  • Self-reactive CD4<sup>+</sup> IL-3<sup>+</sup> T cells amplify autoimmune inflammation in myocarditis by inciting monocyte chemotaxis
    Self-reactive CD4+ IL-3+ T cells amplify autoimmune inflammation in myocarditis by inciting monocyte chemotaxis
    Atsushi Anzai, John E. Mindur, Lennard Halle, Soichi Sano, Jennifer L. Choi, Shun He, Cameron S. McAlpine, Christopher T. Chan, Florian Kahles, Colin Valet, Ashley M. Fenn, Manfred Nairz, Sara Rattik, Yoshiko Iwamoto, DeLisa Fairweather, Kenneth Walsh, Peter Libby, Matthias Nahrendorf, Filip K. Swirski
    Journal of Experimental Medicine Feb 2019, 216 (2) 369-383; DOI: 10.1084/jem.20180722
  • Somatic activating mutations in <em>PIK3CA</em> cause generalized lymphatic anomaly
    Somatic activating mutations in PIK3CA cause generalized lymphatic anomaly
    Lara Rodriguez-Laguna, Noelia Agra, Kristina Ibañez, Gloria Oliva-Molina, Gema Gordo, Noor Khurana, Devon Hominick, María Beato, Isabel Colmenero, Gonzalo Herranz, Juan M. Torres Canizalez, Rebeca Rodríguez Pena, Elena Vallespín, Rubén Martín-Arenas, Ángela del Pozo, Cristina Villaverde, Ana Bustamante, Carmen Ayuso, Pablo Lapunzina, Juan C. Lopez-Gutierrez, Michael T. Dellinger, Victor Martinez-Glez
    Journal of Experimental Medicine Feb 2019, 216 (2) 407-418; DOI: 10.1084/jem.20181353
  • Multiple roles of lymphatic vessels in peripheral lymph node development
    Multiple roles of lymphatic vessels in peripheral lymph node development
    Esther Bovay, Amélie Sabine, Borja Prat-Luri, Sudong Kim, Kyungmin Son, Ann-Helen Willrodt, Cecilia Olsson, Cornelia Halin, Friedemann Kiefer, Christer Betsholtz, Noo Li Jeon, Sanjiv A. Luther, Tatiana V. Petrova
    Journal of Experimental Medicine Nov 2018, 215 (11) 2760-2777; DOI: 10.1084/jem.20180217
  • Piezo1 and G<sub>q</sub>/G<sub>11</sub> promote endothelial inflammation depending on flow pattern and integrin activation
    Piezo1 and Gq/G11 promote endothelial inflammation depending on flow pattern and integrin activation
    Julián Albarrán-Juárez, Andras Iring, ShengPeng Wang, Sayali Joseph, Myriam Grimm, Boris Strilic, Nina Wettschureck, Till F. Althoff, Stefan Offermanns
    Journal of Experimental Medicine Oct 2018, 215 (10) 2655-2672; DOI: 10.1084/jem.20180483
  • Endothelial cell fitness dictates the source of regenerating liver vasculature
    Endothelial cell fitness dictates the source of regenerating liver vasculature
    Mahak Singhal, Xiaoting Liu, Donato Inverso, Kai Jiang, Jianing Dai, Hao He, Susanne Bartels, Weiping Li, Ashik Ahmed Abdul Pari, Nicolas Gengenbacher, Eva Besemfelder, Lijian Hui, Hellmut G. Augustin, Junhao Hu
    Journal of Experimental Medicine Oct 2018, 215 (10) 2497-2508; DOI: 10.1084/jem.20180008
  • Pumping blood with self-reliance and cooperation
    Pumping blood with self-reliance and cooperation
    M. Luisa Iruela-Arispe
    Journal of Experimental Medicine Oct 2018, 215 (10) 2480-2482; DOI: 10.1084/jem.20181537
  • h<em>CALCRL</em> mutation causes autosomal recessive nonimmune hydrops fetalis with lymphatic dysplasia
    hCALCRL mutation causes autosomal recessive nonimmune hydrops fetalis with lymphatic dysplasia
    Duncan I. Mackie, Fuad Al Mutairi, Reema B. Davis, Daniel O. Kechele, Natalie R. Nielsen, Joshua C. Snyder, Marc G. Caron, Harvey J. Kliman, Jonathan S. Berg, John Simms, David R. Poyner, Kathleen M. Caron
    Journal of Experimental Medicine Sep 2018, 215 (9) 2339-2353; DOI: 10.1084/jem.20180528
  • Inhibition of CRTH2-mediated Th2 activation attenuates pulmonary hypertension in mice
    Inhibition of CRTH2-mediated Th2 activation attenuates pulmonary hypertension in mice
    Guilin Chen, Shengkai Zuo, Juan Tang, Caojian Zuo, Daile Jia, Qian Liu, Guizhu Liu, Qian Zhu, Yuanyang Wang, Jian Zhang, Yujun Shen, Dongrui Chen, Ping Yuan, Zhiqiang Qin, Chengchao Ruan, Jue Ye, Xiao-Jian Wang, Yuping Zhou, Pingjin Gao, Peng Zhang, Jinming Liu, Zhi-Cheng Jing, Ankang Lu, Ying Yu
    Journal of Experimental Medicine Aug 2018, 215 (8) 2175-2195; DOI: 10.1084/jem.20171767
  • Cardiac macrophages promote diastolic dysfunction
    Cardiac macrophages promote diastolic dysfunction
    Maarten Hulsmans, Hendrik B. Sager, Jason D. Roh, María Valero-Muñoz, Nicholas E. Houstis, Yoshiko Iwamoto, Yuan Sun, Richard M. Wilson, Gregory Wojtkiewicz, Benoit Tricot, Michael T. Osborne, Judy Hung, Claudio Vinegoni, Kamila Naxerova, David E. Sosnovik, Michael R. Zile, Amy D. Bradshaw, Ronglih Liao, Ahmed Tawakol, Ralph Weissleder, Anthony Rosenzweig, Filip K. Swirski, Flora Sam, Matthias Nahrendorf
    Journal of Experimental Medicine Feb 2018, 215 (2) 423-440; DOI: 10.1084/jem.20171274

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