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Index of Online Supplemental Material for
J. Exp. Med. 10.1084/jem.20081219
Chong et al. Figure S1 Multiple Drosha splice isoforms are expressed in mouse tissues.
Figure S2 Generation of the conditional Drosha allele.
Figure S3 Accumulation of inflammatory cytokine-producing CD4+ T cells in the spleens of aging DroshaF/Δ CD4-cre mice.
Figure S4 Moribund DroshaF/Δ CD4-cre mice do not develop splenomegaly or lymphadenopathy.
Figure S5 Defective TGF-β–induced Foxp3 expression in the absence of Drosha is not caused by thymocyte selection defects.
Figure S6 Enhanced IFN-γ expression in Drosha-deficient CD4+ cells is not caused by thymocyte selection defects.
Figure S7 Induction of IFN-γ expression in Drosha-deficient CD8+ cells.
Figure S8 Foxp3 is not coexpressed with IFN-γ or IL-17A in moribund DroshaF/Δ CD4-cre or DroshaF/Δ Foxp3Cre/Cre(Y) mice.
Figure S9 Drosha-deficient T cells display a partial proliferation defect in response to TCR stimulation or lymphopenia.
Tables S1–S2 (PDF)
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