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Index of Online Supplemental Material for
J. Exp. Med. 10.1084/jem.20071990
Spiller et al.

• Figure S1 Comparative analysis of 1A6 binding to overexpressed and endogenous cell surface TLR4–MD-2 complex by flow cytometry.

• Figure S2 Specificity and inhibitory potential of TLR4–MD-2–specific 1A6.

• Figure S3 Inhibitory and protective activity of TLR4-MD-2-specific 1A6 in vivo.

• Figure S4 TLR4-independent, systemic persistence of CD11b⁺ cells upon systemic 1A6 application and continuous presence of 1A6 on the surface of macrophages upon application in vitro.

• Figure S5 TLR4-dependent T cell activation upon Salmonella enterica infection and enhanced surface TLR2 expression by human monocytes in vivo.

• Figure S6 Overview on procedures applied and findings.

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