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Index of Online Supplemental Material for
J. Exp. Med. 10.1084/jem.20062567
Groom et al. Figure S1 Generation of BAFF Tg mice lacking T cells.
Figure S2 IgG autoantibodies are predominantly IgG2c, IgG2b, and IgG3 in TΔ-BTg mice.
Figure S3 Tissue Ig deposition in TΔ-BTg mice is predominantly IgG2c, IgG2b, and IgG3, with no IgG1.
Figure S4 BAFF enhances TLR-mediated IgG switching and increases TLR7 and TLR9 expression, and BAFF is increased in MyD88--/-- mice.
Figure S5 MyD88-mediated signaling is essential for IgG kidney deposition, basal IgG2c, and IgG2b production, and T cell activation in BAFF Tg mice, but does not alter mDC or pDC activation.
Figure S6 TLR9-deficiency does not alter anti-dsDNA antibody response in BAFF Tg mice.
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